CIC channels: leaving the dark ages on the verge of a new millennium

被引:36
作者
Valverde, MA [1 ]
机构
[1] Univ Pompeu Fabra, Dept Ciencies Expt & Salut, Barcelona, Spain
关键词
D O I
10.1016/S0955-0674(99)80074-X
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The field of molecular physiology of CIC chloride channels has witnessed a tremendous surge in knowledge over the past few years; however, fundamental issues such as the stoichiometry of CIC channels and the identification of pore-lining sequences have only recently begun to be addressed. New studies have also provided important insights into the role of CIC channels in cell volume regulation and their function in intracellular organelles.
引用
收藏
页码:509 / 516
页数:8
相关论文
共 82 条
[1]   STRUCTURE AND FUNCTION OF INHIBITORY GLYCINE RECEPTORS [J].
BETZ, H .
QUARTERLY REVIEWS OF BIOPHYSICS, 1992, 25 (04) :381-394
[2]   Protein kinase C phosphorylation disengages human and mouse-1a P-glycoproteins from influencing the rate of activation of swelling-activated chloride currents [J].
Bond, TD ;
Valverde, MA ;
Higgins, CF .
JOURNAL OF PHYSIOLOGY-LONDON, 1998, 508 (02) :333-340
[3]  
Bond TD, 1998, METHOD ENZYMOL, V292, P359
[4]   Osmosensitive Cl- currents and their relevance to regulatory volume decrease in human intestinal T84 cells:: outwardly vs. inwardly rectifying currents [J].
Bond, TD ;
Ambikapathy, S ;
Mohammad, S ;
Valverde, MA .
JOURNAL OF PHYSIOLOGY-LONDON, 1998, 511 (01) :45-54
[5]   CHARACTERIZATION OF A HUMAN AND MURINE GENE (CLCN3) SHARING SIMILARITIES TO VOLTAGE-GATED CHLORIDE CHANNELS AND TO A YEAST INTEGRAL MEMBRANE-PROTEIN [J].
BORSANI, G ;
RUGARLI, EI ;
TAGLIALATELA, M ;
WONG, C ;
BALLABIO, A .
GENOMICS, 1995, 27 (01) :131-141
[6]   Splicing of α1A subunit gene generates phenotypic variants of P- and Q-type calcium channels [J].
Bourinet, E ;
Soong, TW ;
Sutton, K ;
Slaymaker, S ;
Mathews, E ;
Monteil, A ;
Zamponi, GW ;
Nargeot, J ;
Snutch, TP .
NATURE NEUROSCIENCE, 1999, 2 (05) :407-415
[7]   Evidence for the intracellular location of chloride channel (CIC)-type proteins:: co-localization of CIC-6a and CIC-6c with the sarco/endoplasmic-reticulum Ca2+ pump SERCA2b [J].
Buyse, G ;
Trouet, D ;
Voets, T ;
Missiaen, L ;
Droogmans, G ;
Nilius, B ;
Eggermont, J .
BIOCHEMICAL JOURNAL, 1998, 330 :1015-1021
[8]   Identification of CIC-2-like chloride currents in pig pancreatic acinar cells [J].
Carew, MA ;
Thorn, P .
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1996, 433 (1-2) :84-90
[9]   Extracellular zinc ion inhibits ClC-0 chloride channels by facilitating slow gating [J].
Chen, TY .
JOURNAL OF GENERAL PHYSIOLOGY, 1998, 112 (06) :715-726
[10]   Nonequilibrium gating and voltage dependence of the ClC-0 Cl- channel [J].
Chen, TY ;
Miller, C .
JOURNAL OF GENERAL PHYSIOLOGY, 1996, 108 (04) :237-250