Primary Sjogren's Syndrome Complicated by Sarcoidosis

被引:12
作者
Tokuyasu, Hirokazu [1 ]
Harada, Tomoya [1 ]
Touge, Hirokazu [1 ]
Kawasaki, Yuji [1 ]
Maeda, Ryo [2 ]
Isowa, Noritaka [2 ]
Ohnuma, Hideyuki [3 ]
Miura, Hiroshi [3 ]
Shimizu, Eiji [4 ]
机构
[1] Matsue Red Cross Hosp, Div Resp Med, Matsue, Shimane, Japan
[2] Matsue Red Cross Hosp, Div Thorac Surg, Matsue, Shimane, Japan
[3] Matsue Red Cross Hosp, Div Pathol, Matsue, Shimane, Japan
[4] Tottori Univ, Fac Med, Dept Multidisciplinary Internal Med, Div Med Oncol & Mol Respirol, Yonago, Tottori 683, Japan
关键词
Sjogren's Syndrome; sarcoidosis; pulmonary multiple nodules;
D O I
10.2169/internalmedicine.47.1526
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 51-year-old woman suffered from xerophthalmia and xerostomia for 3 years without being medically examined. In July 2006, she was referred to our hospital for the evaluation of chest roentgenogram showing slight pleural effusion in the right lung. A chest CT scan revealed multiple nodules, enlarged mediastinal and hilar lymph nodes, and bilateral slight pleural effusions. A diagnosis of Sjogren's syndrome was made on the basis of the results of sialography, lip biopsy, Schirmer's test, and elevated titer of antibody to SS-A antigen. Histological examination of the specimen from the nodular lesion by video-assisted thoracoscopic biopsy revealed noncaseating epithelioid cell granuloma containing giant cells, which confirmed the diagnosis of sarcoidosis. Although the coexistence of Sjogren's syndrome and sarcoidosis has been reported occasionally, cases with histological evidence of sarcoidosis have been rare. Pulmonary sarcoidosis should be considered in the differential diagnosis of pulmonary multiple nodules in patients with Sjogren's syndrome.
引用
收藏
页码:2049 / 2052
页数:4
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