共 133 条
[1]
POLYCYTHEMIA-VERA - STEM-CELL AND PROBABLE CLONAL ORIGIN OF DISEASE
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ADAMSON, JW
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FIALKOW, PJ
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MURPHY, S
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PRCHAL, JF
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STEINMANN, L
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NEW ENGLAND JOURNAL OF MEDICINE,
1976, 295 (17)
:913-916

ADAMSON, JW
论文数: 0 引用数: 0
h-index: 0
机构: VET ADM HOSP, SERV MED, HEMATOL SECT, SEATTLE, WA 98108 USA

FIALKOW, PJ
论文数: 0 引用数: 0
h-index: 0
机构: VET ADM HOSP, SERV MED, HEMATOL SECT, SEATTLE, WA 98108 USA

MURPHY, S
论文数: 0 引用数: 0
h-index: 0
机构: VET ADM HOSP, SERV MED, HEMATOL SECT, SEATTLE, WA 98108 USA

PRCHAL, JF
论文数: 0 引用数: 0
h-index: 0
机构: VET ADM HOSP, SERV MED, HEMATOL SECT, SEATTLE, WA 98108 USA

STEINMANN, L
论文数: 0 引用数: 0
h-index: 0
机构: VET ADM HOSP, SERV MED, HEMATOL SECT, SEATTLE, WA 98108 USA
[2]
Critical Role of Jak2 in the Maintenance and Function of Adult Hematopoietic Stem Cells
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Akada, Hajime
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Akada, Saeko
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Hutchison, Robert E.
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Sakamoto, Kazuhito
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Wagner, Kay-Uwe
;
Mohi, Golam
.
STEM CELLS,
2014, 32 (07)
:1878-1889

Akada, Hajime
论文数: 0 引用数: 0
h-index: 0
机构:
SUNY Upstate Med Univ, Dept Pharmacol, Syracuse, NY 13210 USA SUNY Upstate Med Univ, Dept Pharmacol, Syracuse, NY 13210 USA

Akada, Saeko
论文数: 0 引用数: 0
h-index: 0
机构:
SUNY Upstate Med Univ, Dept Pharmacol, Syracuse, NY 13210 USA SUNY Upstate Med Univ, Dept Pharmacol, Syracuse, NY 13210 USA

Hutchison, Robert E.
论文数: 0 引用数: 0
h-index: 0
机构:
SUNY Upstate Med Univ, Dept Pathol, Syracuse, NY 13210 USA SUNY Upstate Med Univ, Dept Pharmacol, Syracuse, NY 13210 USA

Sakamoto, Kazuhito
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Nebraska Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE USA
Univ Nebraska Med Ctr, Dept Pathol & Microbiol, Omaha, NE USA SUNY Upstate Med Univ, Dept Pharmacol, Syracuse, NY 13210 USA

Wagner, Kay-Uwe
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Nebraska Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE USA
Univ Nebraska Med Ctr, Dept Pathol & Microbiol, Omaha, NE USA SUNY Upstate Med Univ, Dept Pharmacol, Syracuse, NY 13210 USA

Mohi, Golam
论文数: 0 引用数: 0
h-index: 0
机构:
SUNY Upstate Med Univ, Dept Pharmacol, Syracuse, NY 13210 USA SUNY Upstate Med Univ, Dept Pharmacol, Syracuse, NY 13210 USA
[3]
Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene activation in the liver
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Alonzi, T
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Maritano, D
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Gorgoni, B
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Rizzuto, G
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Libert, C
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Poli, V
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MOLECULAR AND CELLULAR BIOLOGY,
2001, 21 (05)
:1621-1632

Alonzi, T
论文数: 0 引用数: 0
h-index: 0
机构: Univ Dundee, Wellcome Trust Bioctr, Sch Life Sci, Dundee DD1 5EH, Scotland

Maritano, D
论文数: 0 引用数: 0
h-index: 0
机构: Univ Dundee, Wellcome Trust Bioctr, Sch Life Sci, Dundee DD1 5EH, Scotland

Gorgoni, B
论文数: 0 引用数: 0
h-index: 0
机构: Univ Dundee, Wellcome Trust Bioctr, Sch Life Sci, Dundee DD1 5EH, Scotland

Rizzuto, G
论文数: 0 引用数: 0
h-index: 0
机构: Univ Dundee, Wellcome Trust Bioctr, Sch Life Sci, Dundee DD1 5EH, Scotland

Libert, C
论文数: 0 引用数: 0
h-index: 0
机构: Univ Dundee, Wellcome Trust Bioctr, Sch Life Sci, Dundee DD1 5EH, Scotland

Poli, V
论文数: 0 引用数: 0
h-index: 0
机构: Univ Dundee, Wellcome Trust Bioctr, Sch Life Sci, Dundee DD1 5EH, Scotland
[4]
Modulation of Activation-Loop Phosphorylation by JAK Inhibitors Is Binding Mode Dependent
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Andraos, Rita
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Qian, Zhiyan
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Bonenfant, Debora
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Rubert, Joelle
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Vangrevelinghe, Eric
;
Scheufler, Clemens
;
Marque, Fanny
;
Regnier, Catherine H.
;
De Pover, Alain
;
Ryckelynck, Hugues
;
Bhagwat, Neha
;
Koppikar, Priya
;
Goel, Aviva
;
Wyder, Lorenza
;
Tavares, Gisele
;
Baffert, Fabienne
;
Pissot-Soldermann, Carole
;
Manley, Paul W.
;
Gaul, Christoph
;
Voshol, Hans
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Levine, Ross L.
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Sellers, William R.
;
Hofmann, Francesco
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Radimerski, Thomas
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CANCER DISCOVERY,
2012, 2 (06)
:512-523

Andraos, Rita
论文数: 0 引用数: 0
h-index: 0
机构:
Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Qian, Zhiyan
论文数: 0 引用数: 0
h-index: 0
机构:
Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Bonenfant, Debora
论文数: 0 引用数: 0
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机构: Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Rubert, Joelle
论文数: 0 引用数: 0
h-index: 0
机构:
Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Vangrevelinghe, Eric
论文数: 0 引用数: 0
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机构: Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Scheufler, Clemens
论文数: 0 引用数: 0
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机构:
Novartis Inst BioMed Res, Ctr Prote Chem, CH-4057 Basel, Switzerland Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Marque, Fanny
论文数: 0 引用数: 0
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机构:
Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Regnier, Catherine H.
论文数: 0 引用数: 0
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机构:
Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

De Pover, Alain
论文数: 0 引用数: 0
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机构:
Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Ryckelynck, Hugues
论文数: 0 引用数: 0
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机构:
Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Bhagwat, Neha
论文数: 0 引用数: 0
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机构:
Mem Sloan Kettering Canc Ctr, Dept Med, Human Oncol & Pathogenesis Program, New York, NY 10021 USA
Mem Sloan Kettering Canc Ctr, Dept Med, Leukemia Serv, New York, NY 10021 USA
Gerstner Sloan Kettering Grad Sch Biomed Sci, New York, NY USA Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Koppikar, Priya
论文数: 0 引用数: 0
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机构:
Mem Sloan Kettering Canc Ctr, Dept Med, Human Oncol & Pathogenesis Program, New York, NY 10021 USA
Mem Sloan Kettering Canc Ctr, Dept Med, Leukemia Serv, New York, NY 10021 USA Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Goel, Aviva
论文数: 0 引用数: 0
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机构:
Mem Sloan Kettering Canc Ctr, Dept Med, Human Oncol & Pathogenesis Program, New York, NY 10021 USA
Mem Sloan Kettering Canc Ctr, Dept Med, Leukemia Serv, New York, NY 10021 USA Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Wyder, Lorenza
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机构:
Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Tavares, Gisele
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机构:
Novartis Inst BioMed Res, Ctr Prote Chem, CH-4057 Basel, Switzerland Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Baffert, Fabienne
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机构:
Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Pissot-Soldermann, Carole
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机构: Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Manley, Paul W.
论文数: 0 引用数: 0
h-index: 0
机构: Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Gaul, Christoph
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机构: Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Voshol, Hans
论文数: 0 引用数: 0
h-index: 0
机构: Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Levine, Ross L.
论文数: 0 引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Dept Med, Human Oncol & Pathogenesis Program, New York, NY 10021 USA
Mem Sloan Kettering Canc Ctr, Dept Med, Leukemia Serv, New York, NY 10021 USA Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Sellers, William R.
论文数: 0 引用数: 0
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机构:
Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Hofmann, Francesco
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机构:
Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland

Radimerski, Thomas
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机构:
Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland Novartis Inst BioMed Res, Dis Area Oncol, CH-4057 Basel, Switzerland
[5]
Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms
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Arranz, Lorena
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Sanchez-Aguilera, Abel
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Martin-Perez, Daniel
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Isern, Joan
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Langa, Xavier
;
Tzankov, Alexandar
;
Lundberg, Pontus
;
Muntion, Sandra
;
Tzeng, Yi-Shiuan
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Lai, Dar-Ming
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Schwaller, Juerg
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Skoda, Radek C.
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Mendez-Ferrer, Simon
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NATURE,
2014, 512 (7512)
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Arranz, Lorena
论文数: 0 引用数: 0
h-index: 0
机构:
CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain

Sanchez-Aguilera, Abel
论文数: 0 引用数: 0
h-index: 0
机构:
CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain

Martin-Perez, Daniel
论文数: 0 引用数: 0
h-index: 0
机构:
CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain

Isern, Joan
论文数: 0 引用数: 0
h-index: 0
机构:
CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain

Langa, Xavier
论文数: 0 引用数: 0
h-index: 0
机构:
CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain

Tzankov, Alexandar
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Basel Hosp, CH-4031 Basel, Switzerland CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain

Lundberg, Pontus
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Basel Hosp, CH-4031 Basel, Switzerland CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain

Muntion, Sandra
论文数: 0 引用数: 0
h-index: 0
机构:
IBSAL Hosp Univ Salamanca, Dept Haematol, Salamanca 37007, Spain CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain

Tzeng, Yi-Shiuan
论文数: 0 引用数: 0
h-index: 0
机构:
Natl Taiwan Univ, Taipei 10002, Taiwan CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain

Lai, Dar-Ming
论文数: 0 引用数: 0
h-index: 0
机构:
Natl Taiwan Univ, Taipei 10002, Taiwan CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain

Schwaller, Juerg
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Basel Hosp, CH-4031 Basel, Switzerland CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain

Skoda, Radek C.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Basel Hosp, CH-4031 Basel, Switzerland CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain

Mendez-Ferrer, Simon
论文数: 0 引用数: 0
h-index: 0
机构:
CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain CNIC, Stem Cell Niche Pathophysiol Grp, Madrid 28029, Spain
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The molecular regulation of Janus kinase (JAK) activation
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Babon, Jeffrey J.
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Babon, Jeffrey J.
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h-index: 0
机构:
Walter & Eliza Hall Inst Med Res, Parkville, Vic 3052, Australia
Univ Melbourne, Dept Med Biol, Parkville, Vic 3050, Australia Walter & Eliza Hall Inst Med Res, Parkville, Vic 3052, Australia

Lucet, Isabelle S.
论文数: 0 引用数: 0
h-index: 0
机构:
Walter & Eliza Hall Inst Med Res, Parkville, Vic 3052, Australia
Univ Melbourne, Dept Med Biol, Parkville, Vic 3050, Australia Walter & Eliza Hall Inst Med Res, Parkville, Vic 3052, Australia

Murphy, James M.
论文数: 0 引用数: 0
h-index: 0
机构:
Walter & Eliza Hall Inst Med Res, Parkville, Vic 3052, Australia
Univ Melbourne, Dept Med Biol, Parkville, Vic 3050, Australia Walter & Eliza Hall Inst Med Res, Parkville, Vic 3052, Australia

Nicola, Nicos A.
论文数: 0 引用数: 0
h-index: 0
机构:
Walter & Eliza Hall Inst Med Res, Parkville, Vic 3052, Australia
Univ Melbourne, Dept Med Biol, Parkville, Vic 3050, Australia Walter & Eliza Hall Inst Med Res, Parkville, Vic 3052, Australia

Varghese, Leila N.
论文数: 0 引用数: 0
h-index: 0
机构:
Walter & Eliza Hall Inst Med Res, Parkville, Vic 3052, Australia
Univ Melbourne, Dept Med Biol, Parkville, Vic 3050, Australia Walter & Eliza Hall Inst Med Res, Parkville, Vic 3052, Australia
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Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F
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Bandaranayake, Rajintha M.
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Shan, Yibing
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Shaw, David E.
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Hubbard, Stevan R.
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NATURE STRUCTURAL & MOLECULAR BIOLOGY,
2012, 19 (08)
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Bandaranayake, Rajintha M.
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h-index: 0
机构:
NYU, Sch Med, Struct Biol Program, Kimmel Ctr Biol & Med,Skirball Inst, New York, NY 10012 USA
NYU, Sch Med, Dept Biochem & Mol Pharmacol, New York, NY USA NYU, Sch Med, Struct Biol Program, Kimmel Ctr Biol & Med,Skirball Inst, New York, NY 10012 USA

论文数: 引用数:
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Shan, Yibing
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DE Shaw Res, New York, NY USA NYU, Sch Med, Struct Biol Program, Kimmel Ctr Biol & Med,Skirball Inst, New York, NY 10012 USA

Shaw, David E.
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h-index: 0
机构:
DE Shaw Res, New York, NY USA
Columbia Univ, Ctr Computat Biol & Bioinformat, New York, NY USA NYU, Sch Med, Struct Biol Program, Kimmel Ctr Biol & Med,Skirball Inst, New York, NY 10012 USA

论文数: 引用数:
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Hubbard, Stevan R.
论文数: 0 引用数: 0
h-index: 0
机构:
NYU, Sch Med, Struct Biol Program, Kimmel Ctr Biol & Med,Skirball Inst, New York, NY 10012 USA
NYU, Sch Med, Dept Biochem & Mol Pharmacol, New York, NY USA NYU, Sch Med, Struct Biol Program, Kimmel Ctr Biol & Med,Skirball Inst, New York, NY 10012 USA
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Co-targeting the PI3K/mTOR and JAK2 signalling pathways produces synergistic activity against myeloproliferative neoplasms
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Bartalucci, Niccolo
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Tozzi, Lorenzo
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Bogani, Costanza
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Martinelli, Serena
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Rotunno, Giada
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Villeval, Jean-Luc
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Vannucchi, Alessandro M.
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JOURNAL OF CELLULAR AND MOLECULAR MEDICINE,
2013, 17 (11)
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Bartalucci, Niccolo
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h-index: 0
机构:
Univ Florence, Dept Expt & Clin Med, I-50134 Florence, Italy Univ Florence, Dept Expt & Clin Med, I-50134 Florence, Italy

Tozzi, Lorenzo
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Florence, Dept Expt & Clin Med, I-50134 Florence, Italy Univ Florence, Dept Expt & Clin Med, I-50134 Florence, Italy

Bogani, Costanza
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Florence, Dept Expt & Clin Med, I-50134 Florence, Italy Univ Florence, Dept Expt & Clin Med, I-50134 Florence, Italy

论文数: 引用数:
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Rotunno, Giada
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Florence, Dept Expt & Clin Med, I-50134 Florence, Italy Univ Florence, Dept Expt & Clin Med, I-50134 Florence, Italy

Villeval, Jean-Luc
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h-index: 0
机构:
Inst Gustave Roussy, INSERM, U1009, F-94805 Villejuif, France
Univ Paris 11, Villejuif, France Univ Florence, Dept Expt & Clin Med, I-50134 Florence, Italy

Vannucchi, Alessandro M.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Florence, Dept Expt & Clin Med, I-50134 Florence, Italy Univ Florence, Dept Expt & Clin Med, I-50134 Florence, Italy
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Bartalucci Niccolo, 2013, Clin Lymphoma Myeloma Leuk, V13 Suppl 2, pS307, DOI 10.1016/j.clml.2013.07.011
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Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
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Baxter, EJ
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Scott, LM
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Campbell, PJ
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East, C
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Fourouclas, N
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Swanton, S
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Vassiliou, GS
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Bench, AJ
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Boyd, EM
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Curtin, N
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Scott, MA
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Erber, WN
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Green, AR
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LANCET,
2005, 365 (9464)
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Baxter, EJ
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cambridge, Cambridge Inst Med Res, Dept Haematol, Cambridge CB2 2XY, England

Scott, LM
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cambridge, Cambridge Inst Med Res, Dept Haematol, Cambridge CB2 2XY, England

Campbell, PJ
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cambridge, Cambridge Inst Med Res, Dept Haematol, Cambridge CB2 2XY, England

East, C
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cambridge, Cambridge Inst Med Res, Dept Haematol, Cambridge CB2 2XY, England

Fourouclas, N
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cambridge, Cambridge Inst Med Res, Dept Haematol, Cambridge CB2 2XY, England

Swanton, S
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cambridge, Cambridge Inst Med Res, Dept Haematol, Cambridge CB2 2XY, England

Vassiliou, GS
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cambridge, Cambridge Inst Med Res, Dept Haematol, Cambridge CB2 2XY, England

Bench, AJ
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cambridge, Cambridge Inst Med Res, Dept Haematol, Cambridge CB2 2XY, England

Boyd, EM
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cambridge, Cambridge Inst Med Res, Dept Haematol, Cambridge CB2 2XY, England

Curtin, N
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cambridge, Cambridge Inst Med Res, Dept Haematol, Cambridge CB2 2XY, England

Scott, MA
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cambridge, Cambridge Inst Med Res, Dept Haematol, Cambridge CB2 2XY, England

Erber, WN
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cambridge, Cambridge Inst Med Res, Dept Haematol, Cambridge CB2 2XY, England

Green, AR
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cambridge, Cambridge Inst Med Res, Dept Haematol, Cambridge CB2 2XY, England