Management of severe cutaneous adverse drug reactions to corticosteroids

被引：2

作者：

Waton, J. ^{[1
]}

Baeck, M. ^{[2
]}

Torres, M. ^{[3
]}

Barbaud, A. ^{[1
]}

机构：

[1] CHU Nancy, Serv Dermatol, F-54000 Nancy, France

[2] Hop St Luc, Serv Dermatol, Brussels, Belgique, Belgium

[3] Clin Malaga, Allergy Immunol Serv, Malaga, Spain

来源：

REVUE FRANCAISE D ALLERGOLOGIE | 2013年 / 53卷 / 03期

关键词：

Corticosteroids; Cutaneous adverse drug reactions; Diagnosis; Management; GENERALIZED EXANTHEMATOUS PUSTULOSIS; METHYLPREDNISOLONE SODIUM SUCCINATE; RENAL-TRANSPLANT RECIPIENT; STEVENS-JOHNSON-SYNDROME; SYSTEMIC CORTICOSTEROIDS; INTRAVENOUS METHYLPREDNISOLONE; INTRAARTICULAR INJECTION; ANAPHYLACTIC REACTION; HYPERSENSITIVITY REACTIONS; ALLERGIC HYPERSENSITIVITY;

D O I：

10.1016/j.reval.2013.01.005

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Cutaneous adverse drug reactions to corticosteroids (CS) are rare and unexpected. A clinical study including 64 patients (largest global series) plus a review of the literature has allowed us to determine the specific characteristics of this group of patients: majority feminine, a strong predisposition to multiple drug reactions, the possibility of late-onset urticaria, reactions due to systemic long-acting CS, and the existence of DRESS or acute generalized exanthematous pustulosis. These hypersensivities are observed with all CS. Diagnosis cannot be based on common classifications of contact allergy. Our study of the 64 cases provided guidelines for skin testing, re-introduction of CS, and future management of allergic reactions to systemic CS. (C) 2013 Elsevier Masson SAS. All rights reserved.

引用

页码：298 / 303

页数：6

共 67 条

[1] Cutaneous reactions to injectable corticosteroids [J].