Teaching Enantioselectivity to C-H Bond Functionalizations: Initial Steps of a Rather Long Shot

被引：16
作者：
Cramer, Nicolai [1 ]
机构：
[1] Ecole Polytech Fed Lausanne, EPFL SB ISIC LCSA, BCH 4305, CH-1015 Lausanne, Switzerland
来源：
CHIMIA | 2012年 / 66卷 / 11期
基金：
瑞士国家科学基金会;
关键词：
Asymmetric catalysis; C-H Activation; Ligands; Palladium; Rhodium; BIOLOGICAL-ACTIVITY; FUSED INDOLINES; ACTIVATION; ACCESS; FRAGMENTATIONS; CONSTRUCTION; ARYLATION; ENTRY;
D O I：
10.2533/chimia.2012.869
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The direct functionalization of non-activated C-H bonds, especially in an enantioselective manner, requires metal catalysts equipped with ligands with specifically designed properties. Examples for asymmetric C(sp(2))-H and C(sp(3))-H functionalizations using palladium- and rhodium catalysts are shown. This work was rewarded by the 2012 Werner Prize of the Swiss Chemical Society.
引用
收藏
页码：869 / 872
页数：4
相关论文
共 27 条
123