Teaching Enantioselectivity to C-H Bond Functionalizations: Initial Steps of a Rather Long Shot

被引：16

作者：

Cramer, Nicolai ^{[1
]}

机构：

[1] Ecole Polytech Fed Lausanne, EPFL SB ISIC LCSA, BCH 4305, CH-1015 Lausanne, Switzerland

来源：

CHIMIA | 2012年 / 66卷 / 11期

基金：

瑞士国家科学基金会;

关键词：

Asymmetric catalysis; C-H Activation; Ligands; Palladium; Rhodium; BIOLOGICAL-ACTIVITY; FUSED INDOLINES; ACTIVATION; ACCESS; FRAGMENTATIONS; CONSTRUCTION; ARYLATION; ENTRY;

D O I：

10.2533/chimia.2012.869

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The direct functionalization of non-activated C-H bonds, especially in an enantioselective manner, requires metal catalysts equipped with ligands with specifically designed properties. Examples for asymmetric C(sp(2))-H and C(sp(3))-H functionalizations using palladium- and rhodium catalysts are shown. This work was rewarded by the 2012 Werner Prize of the Swiss Chemical Society.

引用

页码：869 / 872

页数：4

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