A mild and expedient one-pot synthesis of substituted benzimidazoles in water using a phase-transfer catalyst

被引:18
作者
Chakrabarty, Manas [1 ]
Karmakar, Sulakshana [1 ]
Mukherjee, Ratna [1 ]
Arima, Shiho [2 ]
Harigaya, Yoshihiro [2 ]
机构
[1] Bose Inst, Dept Chem, Kolkata 700009, India
[2] Kitasato Univ, Sch Pharmaceut Sci, Minato Ku, Tokyo 108, Japan
来源
MONATSHEFTE FUR CHEMIE | 2009年 / 140卷 / 04期
关键词
Benzimidazoles; Synthesis; N-alkyl/phenyl-o-phenylenediamines; Aryl aldehydes; Phase-transfer catalyst; ECO-FRIENDLY CATALYST; DIELS-ALDER REACTIONS; PROMOTED SYNTHESIS; 2-SUBSTITUTED BENZIMIDAZOLES; SELECTIVE SYNTHESIS; O-PHENYLENEDIAMINE; EFFICIENT; ACID; DERIVATIVES; ALDEHYDES;
D O I
10.1007/s00706-008-0036-z
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
1-Alkyl/phenyl-2-arylbenzimidazoles have been synthesized in very good to excellent yields by a one-pot condensation of N-alkyl/phenyl-o-phenylenediamines with aryl aldehydes in water at room temperature using cetyl-pyridinium bromide as a cheap and eco-friendly catalyst.
引用
收藏
页码:375 / 380
页数:6
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