Review of sn-2 palmitate oil implications for infant health

被引:80
作者
Bar-Yoseph, Fabiana [1 ]
Lifshitz, Yael [1 ]
Cohen, Tzafra [1 ]
机构
[1] Enzymotec Ltd, Kfar Baruch, Israel
来源
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS | 2013年 / 89卷 / 04期
关键词
Sn-2; palmitate; Human milk; Structured triglyceride; FATTY-ACID-COMPOSITION; HUMAN-MILK; QUANTITATIVE ULTRASOUND; POSITIONAL DISTRIBUTION; BONE STRENGTH; TERM INFANTS; HOST-DEFENSE; MUCUS LAYERS; DOUBLE-BLIND; FORMULA;
D O I
10.1016/j.plefa.2013.03.002
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Human milk provides the optimal balanced nutrition for the growing infant in the first months after birth. The human mammary gland has evolved with unusual pathways, resulting in a specific positioning of fatty acids at the outer sn-1 and sn-3, and center sn-2 of the triacylglyceride, which is different from the triglycerides in other human tissues and plasma. The development of structured triglycerides enables mimicking the composition as well as structure of human milk fat in infant formulas. Studies conducted two decades ago, together with very recent studies, have provided increasing evidence that this unusual positioning of 16:0 in human milk triglycerides has a significant role for infant health in different directions, such as fat and calcium absorption, bone health, intestinal flora and infant comfort. This review aims to unravel the relevance of human milk triglyceride sn-2 16:0 for intestinal health and inflammatory pathways and for other post-absorption effects. (c) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:139 / 143
页数:5
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