An outbreak of Burkholderia cepacia bacteremia in a hemodialysis unit, Cadiz, 2014

被引：12

作者：

Montano-Remacha, Carmen ^{[1
]}

Dolores Marquez-Cruz, Maria ^{[2
]}

Hidalgo-Guzman, Pilar ^{[3
]}

Sanchez-Porto, Antonio ^{[4
]}

de Paula Tellez-Perez, Francisco ^{[5
]}

机构：

[1] Sistema Andaluz Salud, Serv Epidemiol, Area Gest Sanitaria Campo de Gibraltar, Algeciras, Spain

[2] Sistema Andaluz Salud, Serv Med Prevent, Area Gest Sanitaria Campo de Gibraltar, La Linea De La Concepcio, Spain

[3] Sistema Andaluz Salud, Serv Nefrol, Area Gest Sanitaria Campo de Gibraltar, Algeciras, Spain

[4] Sistema Andaluz Salud, Microbiol Serv, Area Gest Sanitaria Campo de Gibraltar, La Linea De La Concepcio, Spain

[5] Sistema Andaluz Salud, Serv Enfermedades Infecc, Area Gest Sanitaria Campo de Gibraltar, La Linea De La Concepcio, Spain

来源：

ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA | 2015年 / 33卷 / 10期

关键词：

Cross infection; Disease outbreaks; Burkholderia cepacia; Renal dialysis; Bacteremia; PSEUDOMONAS-CEPACIA; COLONIZATION; INFECTION;

D O I：

10.1016/j.eimc.2015.02.013

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Introduction: In January 2014 a possible outbreak of Burkholderia cepacia bacteremia occurred in a hemodialysis center situated in La Linea de la Concepcion (Cadiz). An investigation was begun to confirm the outbreak, identify the source, and implement control measures. Methods: A descriptive analysis was performed to describe the characteristics of the patients affected with Burkholderia cepacia bacteremia from November 2013 to February 2014. Environmental samples were taken. A molecular typing study was performed using pulsed field gel electrophoresis (SpeI PFGE) and MLST analysis in order to determine the genetic similarity between the isolates. Results: The bacterium was isolated from blood cultures of 7 patients during the study period. Three of the samples (2 of which were also cases) were endoluminal fluid from catheter locks, and 4 chlorhexidine bottle samples. The patients were coincident in 2 of the 6 work shifts. The mean age of the cases was 67 years of whom 57% were women. Human samples and an environmental sample was analyzed and found to be genetically identical (ST653 clone). Conclusions: The analysis confirmed the outbreak of Burkholderia cepacia, with 7 cases among the patients of the hemodialysis center. The outbreak was due to the same strain, probably a common source and secondary transmission from person to person. (C) 2015 Elsevier Espana, S.L.U. and Sociedad Espanola de Enfermedades Infecciosas y Microbiologia Clinica. All rights reserved.

引用

页码：646 / 650

页数：5

共 17 条

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