Disinfection of needleless connectors with chlorhexidine-alcohol provides long-lasting residual disinfectant activity

被引:37
作者
Hong, Haeyeon [1 ,2 ]
Morrow, Debra Forbes [2 ,3 ]
Sandora, Thomas J. [2 ,4 ,5 ]
Priebe, Gregory P. [1 ,2 ,4 ,6 ]
机构
[1] Brigham & Womens Hosp, Dept Med, Div Infect Dis, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Boston, MA USA
[3] Boston Childrens Hosp, Dept Nursing, Boston, MA USA
[4] Boston Childrens Hosp, Dept Med, Div Infect Dis, Boston, MA USA
[5] Boston Childrens Hosp, Dept Lab Med, Boston, MA USA
[6] Boston Childrens Hosp, Dept Anesthesiol Perioperat & Pain Med, Div Crit Care Med, Boston, MA USA
关键词
Central line-associated bloodstream infection; Line maintenance bundle;
D O I
10.1016/j.ajic.2012.10.018
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The optimal disinfection method for needleless connectors (NCs) is unclear. We used an experimental model of microbial NC contamination to test different scrub times (swipe, 5, 15, 30 seconds) of chlorhexidine-alcohol versus alcohol and for residual disinfectant activity. Swipe with alcohol did not adequately disinfect NCs, particularly when contaminated with Staphylococcus aureus or Pseudomonas aeruginosa. With >= 5-second scrub, chlorhexidine-alcohol and alcohol performed similarly, but chlorhexidine-alcohol showed residual disinfectant activity for up to 24 hours. Copyright (C) 2013 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.
引用
收藏
页码:E77 / E79
页数:3
相关论文
共 10 条
  • [1] The effects of needleless connectors on catheter-related bloodstream infections
    Btaiche, Imad F.
    Kovacevich, Debra S.
    Khalidi, Nabil
    Papke, Lorelei F.
    [J]. AMERICAN JOURNAL OF INFECTION CONTROL, 2011, 39 (04) : 277 - 283
  • [2] A randomized, prospective clinical trial to assess the potential infection risk associated with the PosiFlow® needleless connector
    Casey, AL
    Worthington, T
    Lambert, PA
    Quinn, D
    Faroqui, MH
    Elliott, TSJ
    [J]. JOURNAL OF HOSPITAL INFECTION, 2003, 54 (04) : 288 - 293
  • [3] Identification of psl, a locus encoding a potential exopolysaccharide that is essential for Pseudomonas aeruginosa PAO1 biofilm formation
    Jackson, KD
    Starkey, M
    Kremer, S
    Parsek, MR
    Wozniak, DJ
    [J]. JOURNAL OF BACTERIOLOGY, 2004, 186 (14) : 4466 - 4475
  • [4] Kaler WCR., 2007, JAVA, V12, P140, DOI [10.2309/java.12-3-9, DOI 10.2309/JAVA.12-3-9]
  • [5] Disinfection of needleless catheter connectors and access ports with alcohol may not prevent microbial entry: The promise of a novel antiseptic-barrier cap
    Menyhay, Steve Z.
    Maki, Dennis G.
    [J]. INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2006, 27 (01) : 23 - 27
  • [6] Reducing PICU Central Line-Associated Bloodstream Infections: 3-Year Results
    Miller, Marlene R.
    Niedner, Matthew F.
    Huskins, W. Charles
    Colantuoni, Elizabeth
    Yenokyan, Gayane
    Moss, Michele
    Rice, Tom B.
    Ridling, Debra
    Campbell, Deborah
    Brilli, Richard J.
    [J]. PEDIATRICS, 2011, 128 (05) : E1077 - E1083
  • [7] O'Grady NP, 2011, CLIN INFECT DIS, V52, pE162, DOI [10.1016/j.ajic.2011.01.003, 10.1093/cid/cir257]
  • [8] Adequate Disinfection of a Split-Septum Needleless Intravascular Connector with a 5-Second Alcohol Scrub
    Rupp, Mark E.
    Yu, Stephanie
    Huerta, Tomas
    Cavalieri, R. Jennifer
    Alter, Roxanne
    Fey, Paul D.
    Van Schooneveld, Trevor
    Anderson, James R.
    [J]. INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2012, 33 (07) : 661 - 665
  • [9] Scrub the Hub Cleaning Duration and Reduction in Bacterial Load on Central Venous Catheters
    Simmons, Sarah
    Bryson, Celestina
    Porter, Susan
    [J]. CRITICAL CARE NURSING QUARTERLY, 2011, 34 (01) : 31 - 35
  • [10] A fall in bloodstream infections followed a change to 2% chlorhexidine in 70% isopropanol for catheter connection antisepsis: A pediatric single center before/after study on a hemopoietic stem cell transplant ward
    Soothill, James S.
    Bravery, Karen
    Ho, Anne
    Macqueen, Susan
    Collins, Jane
    Lock, Paul
    [J]. AMERICAN JOURNAL OF INFECTION CONTROL, 2009, 37 (08) : 626 - 630