RESTORATION OF HCV-SPECIFIC T CELLS FOLLOWING DAA THERAPY IN ACUTE HCV INFECTION-SUPPORT FOR TREATMENT OF ACUTE INFECTION.

被引:0
作者
Casey, Julia [1 ]
MacParland, Sonya [2 ]
Zahoor, Atif [3 ]
Janssen, Harry L. A. [2 ]
Matthews, Gail [4 ]
Marks, Pip [4 ]
Grebely, Jason [4 ]
Dore, Gregory [5 ]
Hansen, Bettina E. [6 ]
Kaul, Rupert [7 ]
Chua, Conan [8 ]
Gehring, Adam J. [9 ]
Feld, Jordan J. [10 ]
机构
[1] Univ Toronto, Inst Med Sci, Toronto, ON, Canada
[2] Univ Hlth Network, Toronto, ON, Canada
[3] Toronto Gen Hosp Res Inst, Toronto, ON, Canada
[4] Unsw, Kirby Inst, Sydney, NSW, Australia
[5] Kirby Inst, Kensington, NSW, Australia
[6] Univ Hlth Network, Toronto Ctr Liver Dis, Toronto Gen Hosp, Toronto, ON, Canada
[7] Univ Toronto, Med, Toronto, ON, Canada
[8] Univ Toronto, Toronto, ON, Canada
[9] Univ Hlth Network, Toronto Ctr Liver Dis, Toronto, ON, Canada
[10] Univ Hlth Network, Toronto Ctr Liver Dis, Viral Hepatitis Care Network VIRCAN, Toronto, ON, Canada
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
1005
引用
收藏
页码:613A / 614A
页数:2
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Culbertson, N ;
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Rosen, HR .
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