'Smart' polymers and what they could do in biotechnology and medicine

被引：688
作者：
Galaev, IY [1 ]
Mattiasson, B [1 ]
机构：
[1] Lund Univ, Dept Biotechnol, Ctr Chem & Chem Engn, SE-22100 Lund, Sweden
来源：
TRENDS IN BIOTECHNOLOGY | 1999年 / 17卷 / 08期
关键词：
D O I：
10.1016/S0167-7799(99)01345-1
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Stimulus-responsive or 'smart' polymers undergo strong conformational changes when only small changes in the environment (e,g. pH, temperature, ionic strength) occur. These changes result in phase separation from aqueous solution or order-of-magnitude changes in hydrogel size. Smart polymers are used in bioseparation and drug delivery, for the development of new biocatalysts, as biomimetic actuators, and as surfaces with switchable hydrophobic-hydrophilic properties.
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页码：335 / 340
页数：6
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