Electrochemical determination of glutathione based on an electrodeposited nickel oxide nanoparticles-modified glassy carbon electrode

被引：27

作者：

Yuan, Baiqing ^{[1
]}

Zeng, Xiaoying ^{[1
,2
]}

Deng, Dehua ^{[1
]}

Xu, Chunying ^{[1
]}

Liu, Lin ^{[1
]}

Zhang, Jiayu ^{[1
]}

Gao, Yan ^{[1
]}

Pang, Huan ^{[1
,3
]}

机构：

[1] Anyang Normal Univ, Coll Chem & Chem Engn, Anyang 455000, Henan, Peoples R China

[2] Zhengzhou Univ, Sch Pharmaceut Sci, Zhengzhou 450001, Henan, Peoples R China

[3] Nanjing Univ, State Key Lab Coordinat Chem, Nanjing 210093, Jiangsu, Peoples R China

来源：

ANALYTICAL METHODS | 2013年 / 5卷 / 07期

基金：

美国国家科学基金会;

关键词：

PERFORMANCE LIQUID-CHROMATOGRAPHY; QUINONE MODIFIED ELECTRODE; L-CYSTEINE; AMPEROMETRIC DETERMINATION; CAPILLARY-ELECTROPHORESIS; GRAPHITE ELECTRODE; PHYSIOLOGICAL PH; THIOLS; BIOSENSOR; OXIDATION;

D O I：

10.1039/c3ay26536f

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An electrodeposited nickel oxide nanoparticles (NiONPs)-modified glassy carbon (GC) electrode is presented for the first time and used for electrochemical determination of glutathione (GSH). The NiONPs/GC electrode showed a low oxidation potential toward GSH and a wide linear range for its analysis. Different forms of nickel oxide, electrochemically synthesized in different pH buffer solutions, were investigated for the electrochemical oxidation of GSH. The presented sensor was also applied in the analysis of GSH in the presence of uric acid (UA). In addition, the effects of other interfering species including ascorbic acid (AA), dopamine (DA) and glucose were examined and discussed in detail.

引用

页码：1779 / 1783

页数：5

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