PD-1 abrogates the prolonged persistence of CD8+ CAR-T cells with 4-1BB co-stimulation

被引:13
|
作者
Li, Feng [1 ,2 ,3 ,4 ]
Zhang, Zhen [1 ,2 ,3 ,4 ]
Xuan, Yujing [1 ,2 ,3 ]
Zhang, Daiqun [1 ,2 ,3 ,5 ]
Liu, Jinyan [1 ,2 ,3 ]
Li, Aitian [1 ,2 ,3 ]
Wang, Shumin [1 ,2 ,3 ]
Li, Ting [1 ,2 ,3 ]
Shi, Xiaojuan [1 ,2 ,3 ]
Zhang, Yi [1 ,2 ,3 ,4 ,5 ]
机构
[1] Zhengzhou Univ, Affiliated Hosp 1, Biotherapy Ctr, Zhengzhou, Henan, Peoples R China
[2] Zhengzhou Univ, Affiliated Hosp 1, Canc Ctr, Zhengzhou, Henan, Peoples R China
[3] State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou, Henan, Peoples R China
[4] Henan Key Lab Tumor Immunol & Biotherapy, Zhengzhou, Henan, Peoples R China
[5] Zhengzhou Univ, Sch Life Sci, Zhengzhou, Henan, Peoples R China
基金
中国国家自然科学基金;
关键词
D O I
10.1038/s41392-020-00277-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页数:4
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