MRI for attenuation correction in PET: methods and challenges

被引:173
作者
Wagenknecht, Gudrun [1 ]
Kaiser, Hans-Juergen [2 ]
Mottaghy, Felix M. [2 ,3 ]
Herzog, Hans [4 ]
机构
[1] Forschungszentrum Julich, Cent Inst Elect, D-52425 Julich, Germany
[2] Rhein Westfal TH Aachen, Dept Nucl Med, Univ Hosp, Aachen, Germany
[3] Maastricht Univ, Dept Nucl Med, Med Ctr, Maastricht, Netherlands
[4] Forschungszentrum Julich, Inst Neurosci & Med, D-52425 Julich, Germany
关键词
PET/MR; MR-based attenuation correction; Brain; Whole body; Coils; Truncation artefact; DIXON TECHNIQUE; SURFACE COILS; CT IMAGES; PET/MRI; SEGMENTATION; SYSTEMS; DESIGN; ATLAS; RECONSTRUCTION; DECOMPOSITION;
D O I
10.1007/s10334-012-0353-4
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
In current combined PET/MR systems, PET attenuation correction is based on MRI, since the small bore inside MRI systems and the strong magnetic field do not permit a rotating PET transmission source or a CT device to be integrated. Unlike CT measurements in PET/CT scanners, the MR signal is not directly correlated to tissue density and thus cannot be converted by a simple transformation of intensity values. Various approaches have been developed based on templates, atlas information, direct segmentation of T1-weighted MR images, or segmentation of images from special MR sequences. The advantages and disadvantages of these approaches as well as additional challenges will be discussed in this review.
引用
收藏
页码:99 / 113
页数:15
相关论文
共 60 条
[1]  
Akbarzadeh A, 2011, IEEE NUCL SCI CONF R, P2524, DOI 10.1109/NSSMIC.2011.6152682
[2]  
[Anonymous], LECT NOTES COMPUTER
[3]  
[Anonymous], 1989, ICRU REPORT 44
[4]  
Ashburner J, 1999, HUM BRAIN MAPP, V7, P254, DOI 10.1002/(SICI)1097-0193(1999)7:4<254::AID-HBM4>3.0.CO
[5]  
2-G
[6]   MRI-Based Attenuation Correction for Hybrid PET/MRI Systems: A 4-Class Tissue Segmentation Technique Using a Combined Ultrashort-Echo-Time/Dixon MRI Sequence [J].
Berker, Yannick ;
Franke, Jochen ;
Salomon, Andre ;
Palmowski, Moritz ;
Donker, Henk C. W. ;
Temur, Yavuz ;
Mottaghy, Felix M. ;
Kuhl, Christiane ;
Izquierdo-Garcia, David ;
Fayad, Zahi A. ;
Kiessling, Fabian ;
Schulz, Volkmar .
JOURNAL OF NUCLEAR MEDICINE, 2012, 53 (05) :796-804
[7]   PET attenuation coefficients from CT images: experimental evaluation of the transformation of CT into PET 511-keV attenuation coefficients [J].
Burger, C ;
Goerres, G ;
Schoenes, S ;
Buck, A ;
Lonn, AHR ;
von Schulthess, GK .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2002, 29 (07) :922-927
[8]   Method for transforming CT images for attenuation correction in PET/CT imaging [J].
Carney, JPJ ;
Townsend, DW ;
Rappoport, V ;
Bendriem, B .
MEDICAL PHYSICS, 2006, 33 (04) :976-983
[9]   Toward Implementing an MRI-Based PET Attenuation-Correction Method for Neurologic Studies on the MR-PET Brain Prototype [J].
Catana, Ciprian ;
van der Kouwe, Andre ;
Benner, Thomas ;
Michel, Christian J. ;
Hamm, Michael ;
Fenchel, Matthias ;
Fischl, Bruce ;
Rosen, Bruce ;
Schmand, Matthias ;
Sorensen, A. Gregory .
JOURNAL OF NUCLEAR MEDICINE, 2010, 51 (09) :1431-1438
[10]   Design and construction of a realistic digital brain phantom [J].
Collins, DL ;
Zijdenbos, AP ;
Kollokian, V ;
Sled, JG ;
Kabani, NJ ;
Holmes, CJ ;
Evans, AC .
IEEE TRANSACTIONS ON MEDICAL IMAGING, 1998, 17 (03) :463-468