Fluid-structure interaction in deformable microchannels

被引:63
作者
Chakraborty, Debadi [3 ]
Prakash, J. Ravi [3 ]
Friend, James [1 ,2 ]
Yeo, Leslie [1 ]
机构
[1] RMIT Univ, Sch Elect & Comp Engn, Micro Nanophys Res Lab, Melbourne, Vic 3000, Australia
[2] Melbourne Ctr Nanofabricat, Clayton, Vic 3800, Australia
[3] Monash Univ, Dept Chem Engn, Melbourne, Vic 3800, Australia
基金
澳大利亚研究理事会;
关键词
WALLED COLLAPSIBLE-TUBE; FREE-SURFACE FLOWS; MICROFLUIDIC SYSTEMS; NUMERICAL-SIMULATION; SOFT LITHOGRAPHY; ELASTIC-MODULUS; STEADY FLOW; CHANNEL; INSTABILITY; POLY(DIMETHYLSILOXANE);
D O I
10.1063/1.4759493
中图分类号
O3 [力学];
学科分类号
08 ; 0801 ;
摘要
A polydimethylsiloxane microfluidic device composed of a single microchannel with a thin flexible layer present over a short length along one side of the channel was fabricated and modelled in order to investigate the complex fluid-structure interaction that arises between a flowing fluid and a deformablewall. Experimental measurements of thin layer deformation and pressure drop are compared with predictions of two- and three-dimensional computational models that numerically solve the coupled set of equations governing both the elasticity of the thin layer and the fluid. It is shown that the two-dimensional model, which assumes the flexible thin layer comprises an infinitely wide elastic beam of finite thickness, reasonably approximates a three-dimensional model, and is in excellent agreement with experimental observations of the thin layer profile when the width of the thin layer is beyond a critical value, roughly twice the length of the thin layer. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4759493]
引用
收藏
页数:21
相关论文
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[21]   Fabrication of microfluidic devices using polydimethylsiloxane [J].
Friend, James ;
Yeo, Leslie .
BIOMICROFLUIDICS, 2010, 4 (02)
[22]   Optimization of poly-di-methyl-siloxane (PDMS) substrates for studying cellular adhesion and motility [J].
Fuard, D. ;
Tzvetkova-Chevolleau, T. ;
Decossas, S. ;
Tracqui, P. ;
Schiavone, P. .
MICROELECTRONIC ENGINEERING, 2008, 85 (5-6) :1289-1293
[23]   Instability of creeping Couette flow past a neo-Hookean solid [J].
Gkanis, V ;
Kumar, S .
PHYSICS OF FLUIDS, 2003, 15 (10) :2864-2871
[24]   Steady finite-Reynolds-number flows in three-dimensional collapsible tubes [J].
Hazel, AL ;
Heil, M .
JOURNAL OF FLUID MECHANICS, 2003, 486 :79-103
[25]  
Heil M., 2003, FLOW HIGHLY COMPLIAN, P15, DOI DOI 10.1007/978-94-017-0415-1_2
[26]   Flexible Microfluidic Device for Mechanical Property Characterization of Soft Viscoelastic Solids Such as Bacterial Biofilms [J].
Hohne, Danial N. ;
Younger, John G. ;
Solomon, Michael J. .
LANGMUIR, 2009, 25 (13) :7743-7751
[27]   A tunable micro filter modulated by pneumatic pressure for cell separation [J].
Huang, Song-Bin ;
Wu, Min-Hsien ;
Lee, Gwo-Bin .
SENSORS AND ACTUATORS B-CHEMICAL, 2009, 142 (01) :389-399
[28]   Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients [J].
Irimia, D ;
Liu, SY ;
Tharp, WG ;
Samadani, A ;
Toner, M ;
Poznansky, MC .
LAB ON A CHIP, 2006, 6 (02) :191-198
[29]   Cell handling using microstructured membranes [J].
Irimia, D ;
Toner, M .
LAB ON A CHIP, 2006, 6 (03) :345-352
[30]  
Johnson K.L., 2003, CONTACT MECH