Efficient Synthesis of Propargylamines in Aqueous Media Catalyzed by Au Nanoparticles under Ambient Temperature

被引：6

作者：

Moghaddam, Firouz Matloubi ^{[1
]}

Pourkaveh, Raheleh ^{[1
]}

机构：

[1] Sharif Univ Technol, Lab Organ Synth & Nat Prod, Dept Chem, Azadi St,POB 111559516, Tehran, Iran

来源：

CHEMISTRYSELECT | 2018年 / 3卷 / 07期

关键词：

Gold nanocatalyst; Montmorillonite; Proline; Propargylamine; Room temperature; 3-COMPONENT COUPLING REACTION; GOLD NANOPARTICLES; MULTICOMPONENT REACTION; ALDEHYDE; ALKYNE; AMINE; COMPLEX; ACTIVATION; WATER;

D O I：

10.1002/slct.201703096

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An eco-friendly gold-based catalyst supported on proline decorated montmorillonite was synthesized. The catalyst was characterized by combination of Fourier-transform infrared spectroscopy (FT-IR), Field Emission Scanning Electron Microscopy (FE-SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), Brunauer-Emmett Teller (BET) surface area analysis, Ultraviolet-visible spectroscopy (UV-Vis), Energy-dispersive X-ray spectroscopy (EDX), thermo gravimetric analysis (TGA) and atomic absorption spectroscopy (AAS) techniques. The synthesized catalyst was found to be a highly efficient heterogeneous nanocatalyst for multi component A(3) coupling reaction of aldehyde, amine and alkyne in water as a green solvent at room temperature. This novel catalyst promotes multicomponent reaction of a large library of functional substrates under mild and sustainable conditions (water as a green solvent at ambient temperature). In addition, the catalyst could be easily recovered by simple filtration and reused for at least 6 cycles without losing its activity.

引用

页码：2053 / 2058

页数：6

共 30 条

[1]

Anand N., 2013, APPL CATAL A-GEN, V119, P454

[2] Neuroprotective and neurorestorative potential of propargylamine derivatives in ageing: focus on mitochondrial targets [J].