Semiconducting Polymer Nanoprobe for In Vivo Imaging of Reactive Oxygen and Nitrogen Species

被引：204
|
作者：
Pu, Kanyi [1 ,2 ]
Shuhendler, Adam J. [1 ,2 ]
Rao, Jianghong [1 ,2 ]
机构：
[1] Stanford Univ, Dept Radiol, Mol Imaging Program Stanford, Stanford, CA 94305 USA
[2] Stanford Univ, Dept Chem, Mol Imaging Program Stanford, Stanford, CA 94305 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 39期
关键词：
biosensors; imaging agents; nanoparticles; polymers; reactive oxygen and nitrogen species; FLUORESCENT-PROBES; QUANTUM DOTS; NITRIC-OXIDE; DESIGN; NANOPARTICLES; DEGRADATION; MECHANISMS; DYES;
D O I：
10.1002/anie.201303420
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Semiconducting polymer nanoparticles are used as a free-radical inert and light-harvesting nanoplatform for in vivo molecular imaging of reactive oxygen and nitrogen species (RONS). This nanoprobe permits detection of RONS in the microenvironment of spontaneous bacterial infection (see picture; FRET=fluorescence resonance energy transfer). Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：10325 / 10329
页数：5
相关论文
共 50 条
  • [31] Interactions between nitric oxide, oxygen, reactive oxygen species and reactive nitrogen species
    Brown, G. C.
    Borutaite, V.
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2006, 34 : 953 - 956
  • [32] Porous CuxCoyS Supraparticles for In Vivo Telomerase Imaging and Reactive Oxygen Species Generation
    Li, Si
    Xu, Liguang
    Hao, Changlong
    Sun, Maozhong
    Wu, Xiaoling
    Kuang, Hua
    Xu, Chuanlai
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 58 (52) : 19067 - 19072
  • [33] Electrochemical micro- and nanobiosensors for in vivo reactive oxygen/nitrogen species measurement in the brain
    Beigloo, Fatemeh
    Khoshkar-Vandi, Samira Amiri
    Pourmand, Elham
    Heydari, Mona
    Molaabasi, Fatemeh
    Gharib, Nima
    Zare, Yasser
    Rhee, Kyong Yop
    Park, Soo-Jin
    NANOTECHNOLOGY REVIEWS, 2023, 12 (01)
  • [34] An all-electron acceptor-based semiconducting polymer nanoprobe for in vivo high brightness NIR-II fluorescence imaging
    Xiao, Shuyi
    Lv, Zhuang
    Lin, Yimu
    Chen, Liang
    DYES AND PIGMENTS, 2024, 224
  • [35] IMAGING REACTIVE OXYGEN SPECIES IN ASTHMA
    VACHIER, I
    LEDOUCEN, C
    LOUBATIERE, J
    DAMON, M
    TEROUANNE, B
    NICOLAS, JC
    CHANEZ, P
    GODARD, P
    JOURNAL OF BIOLUMINESCENCE AND CHEMILUMINESCENCE, 1994, 9 (03): : 171 - 175
  • [36] PET imaging of reactive oxygen species
    Shoghi, Kooresh
    Zhou, Dong
    Chu, Wenhua
    Chepetan, Andre
    Dugan, Laura
    Gropler, Robert
    Mach, Robert
    JOURNAL OF NUCLEAR MEDICINE, 2012, 53
  • [37] Advances in Imaging Reactive Oxygen Species
    Espinoza, Eli M.
    Roise, Joachim Justad
    Li, I-Che
    Das, Riddha
    Murthy, Niren
    JOURNAL OF NUCLEAR MEDICINE, 2021, 62 (04) : 457 - 461
  • [38] Self-Immolative Polymer-Based Chemiluminescent Nanoparticles for Long-Term In Vivo Imaging of Reactive Oxygen Species
    Jeon, Jueun
    You, Dong Gil
    Dey, Anup
    Yoon, Been
    Li, Yuce
    Park, Jae Hyung
    CHEMISTRY OF MATERIALS, 2022, 34 (17) : 7741 - 7749
  • [39] Recent advances of semiconducting polymer nanoparticles in in vivo molecular imaging
    Pu, Kanyi
    Chattopadhyay, Niladri
    Rao, Jianghong
    JOURNAL OF CONTROLLED RELEASE, 2016, 240 : 312 - 322
  • [40] Reactive oxygen and nitrogen species: Friends or foes?
    Zorov, DB
    Bannikova, SY
    Belousov, VV
    Vyssokikh, MY
    Zorova, LD
    Isaev, NK
    Krasnikov, BF
    Krasnikov, BF
    Plotnikov, EY
    BIOCHEMISTRY-MOSCOW, 2005, 70 (02) : 215 - 221
12345