Glabretal-type triterpenoids from Dysoxylum mollissimum

被引:9
作者
Ragasa, Consolacion Y. [1 ,2 ]
Torres, Oscar B. [1 ,2 ]
Bernardo, Leonisa O. [3 ]
Mandia, Emelina H. [2 ,4 ]
Don, Ming-Jaw [5 ]
Shen, Chien-Chang [5 ]
机构
[1] De La Salle Univ, Dept Chem, Manila 1004, Philippines
[2] De La Salle Univ, Ctr Nat Sci & Ecol Res, Manila 1004, Philippines
[3] Southern Luzon State Univ, Quezon City 4328, Philippines
[4] De La Salle Univ, Dept Biol, Manila 1004, Philippines
[5] Natl Res Inst Chinese Med, Taipei 112, Taiwan
关键词
Dysoxylum hainanense; Dysoxylum mollissimum subsp mollissimum; Meliaceae; Dysoxylumglabretol A; Dysoxylumglabretol B; Glabretal triterpenoids; TIRUCALLANE TRITERPENOIDS; CONSTITUENTS; LIMONOIDS; BARK;
D O I
10.1016/j.phytol.2013.06.010
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Dysoxylum mollissimum Blume, the accepted name of the species known by more than a dozen names has been extensively studied for its chemical constituents under the name Dysoxylum hainanense Merr. Congruent with the observation that the chemical constituents of this species might be affected by its geographic distribution, the leaf samples of this species from Quezon Province, Philippines were investigated. The dichloromethane extract of the air-dried leaves of D. mollissimum Blume afforded four new glabretal-type triterpenoids (1a-2b) along with the known compounds, 24,25-epoxy-3 beta,23-dihydroxy-7-tirucallene (3), squalene, polyprenol, linoleic acid and lutein. The structures of 1a-2b were elucidated by extensive 1D and 2D NMR spectroscopy and confirmed by mass spectrometry. (C) 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:514 / 518
页数:5
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