Blood pressure regulation XI: overview and future research directions

被引：31

作者：

Raven, Peter B. ^{[1
]}

Chapleau, Mark W. ^{[2
,3
,4
]}

机构：

[1] Univ North Texas Hlth Sci Ctr, Dept Integrat Physiol & Anat, Ft Worth, TX 76107 USA

[2] Univ Iowa, Dept Internal Med, Iowa City, IA 52242 USA

[3] Univ Iowa, Dept Mol Physiol & Biophys, Iowa City, IA USA

[4] Vet Affairs Med Ctr, Iowa City, IA 52242 USA

来源：

EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY | 2014年 / 114卷 / 03期

关键词：

Arterial baroreflex resetting; Cardiac output; Hemodynamic responses; Hypertension; Reactive oxygen species; Set-point theory; Operating point; Total peripheral resistance; NUCLEUS-TRACTUS-SOLITARII; NEUROGENIC HYPERTENSION; NITRIC-OXIDE; VASCULAR INFLAMMATION; OXIDATIVE STRESS; HEART-FAILURE; BRAIN-STEM; EXERCISE; BAROREFLEX; RISK;

D O I：

10.1007/s00421-014-2823-z

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

While the importance of regulating arterial blood pressure within a 'normal' range is widely appreciated, the definition of 'normal' and the means by which humans and other species regulate blood pressure under various conditions remain hotly debated. The effects of diverse physiological, pathological and environmental challenges on blood pressure and the mechanisms that attempt to maintain it at an optimal level are reviewed and critically analyzed in a series of articles published in this themed issue of the European Journal of Applied Physiology. We summarize here the major points made in these reviews, with emphasis on unifying concepts of regulatory mechanisms and future directions for research.

引用

页码：579 / 586

页数：8

共 38 条

[1] Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease [J].

Aslan, M ;

Ryan, TM ;

Adler, B ;

Townes, TM ;

Parks, DA ;

Thompson, JA ;

Tousson, A ;

Gladwin, MT ;

Patel, RP ;

Tarpey, MM ;

Batinic-Haberle, I ;

White, CR ;

Freeman, BA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (26) :15215-15220

[2] Blood pressure regulation VII. The "morning surge" in blood pressure: measurement issues and clinical significance [J].

Atkinson, Greg ;

Batterham, Alan M. ;

Kario, Kazuomi ;

Taylor, Chloe E. ;

Jones, Helen .

EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, 2014, 114 (03) :521-529

[3]

BRISTOW JD, 1971, CIRC RES, V28, P582

[4] Maximal muscular vascular conductances during whole body upright exercise in humans [J].

Calbet, JAL ;

Jensen-Urstad, M ;

van Hall, G ;

Holmberg, HC ;

Rosdahl, H ;

Saltin, B .

JOURNAL OF PHYSIOLOGY-LONDON, 2004, 558 (01) :319-331

[5] Organization for physiological homeostasis [J].

Cannon, WB .

PHYSIOLOGICAL REVIEWS, 1929, 9 (03) :399-431

[6]

Chapleau MW., 2012, Primer on the autonomic nervous system, V3rd, P161, DOI DOI 10.1016/B978-0-12-386525-0.00033-0

[7]

Eiken O, 2014, EUR J APPL PHYSL

[8] Human investigations into the arterial and cardiopulmonary baroreflexes during exercise [J].

Fadel, Paul J. ;

Raven, Peter B. .

EXPERIMENTAL PHYSIOLOGY, 2012, 97 (01) :39-50

[9] Therapeutic strategies for targeting excessive central sympathetic activation in human hypertension [J].

Fisher, James P. ;

Fadel, Paul J. .

EXPERIMENTAL PHYSIOLOGY, 2010, 95 (05) :572-580

[10] Central sympathetic overactivity: Maladies and mechanisms [J].

Fisher, James P. ;

Young, Colin N. ;

Fadel, Paul J. .

AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, 2009, 148 (1-2) :5-15

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