Gold-Catalyzed Mannich Addition Reactions of 1,3-Dicarbonyl Compounds with N-Protected Imines

被引：7

作者：

Delgado-Rebollo, Manuela ^{[1
]}

Moreno, Rocio ^{[1
]}

Fructos, Manuel R. ^{[1
]}

Prieto, Auxiliadora ^{[2
]}

机构：

[1] Univ Huelva, Ctr Invest Quim Sostenible, Dept Quim & Ciencia Mat, Lab Catalisis Homogenea,Unidad Asociada,CSIC, Huelva 21071, Spain

[2] Univ Huelva, Dept Ingn Quim Quim Fis & Quim Organ, Huelva 21071, Spain

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 2013卷 / 01期

关键词：

Gold; Mannich bases; Carbene ligands; Homogeneous catalysis; ASYMMETRIC ADDITION; ACID;

D O I：

10.1002/ejoc.201201252

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first (N-heterocyclic carbene) Au-I-catalyzed Mannich addition reactions of N-protected imines with different 1,3-dicarbonyl compounds are described. IPrAuNTf2 was proven to be an efficient catalyst for the reactions of beta-keto esters and 1,3-diketones with N-sulfonylimines to afford the desired beta-amino carbonyl compounds in good yields under very mild conditions.

引用

页码：31 / 34

页数：4

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