Surface functionalization of nanoparticles for nanomedicine

被引：615
作者：
Mout, Rubul [1 ]
Moyano, Daniel F. [1 ]
Rana, Subinoy [1 ]
Rotello, Vincent M. [1 ]
机构：
[1] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA
来源：
CHEMICAL SOCIETY REVIEWS | 2012年 / 41卷 / 07期
基金：
美国国家卫生研究院;
关键词：
MODIFIED SILICA NANOPARTICLES; MAGNETIC-RESONANCE DETECTION; GOLD NANOPARTICLES; IN-VIVO; COLORIMETRIC DETECTION; OPTICAL-PROPERTIES; CELL-SURFACE; NANO-FLARES; CANCER; DNA;
D O I：
10.1039/c2cs15294k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Control of interactions between nanoparticles and biosystems is essential for the effective utilization of these materials in biomedicine. A wide variety of nanoparticle surface structures have been developed for imaging, sensing, and delivery applications. In this research Highlight, we will emphasize advances in tailoring nanoparticle interfaces for implementation in nanomedicine.
引用
收藏
页码：2539 / 2544
页数：6
相关论文
共 60 条
[1]   Organization of 'nanocrystal molecules' using DNA [J].
Alivisatos, AP ;
Johnsson, KP ;
Peng, XG ;
Wilson, TE ;
Loweth, CJ ;
Bruchez, MP ;
Schultz, PG .
NATURE, 1996, 382 (6592) :609-611
[2]   Cell surface-based differentiation of cell types and cancer states using a gold nanoparticle-GFP based sensing array [J].
Bajaj, Avinash ;
Rana, Subinoy ;
Miranda, Oscar R. ;
Yawe, Joseph C. ;
Jerry, D. Joseph ;
Bunz, Uwe H. F. ;
Rotello, Vincent M. .
CHEMICAL SCIENCE, 2010, 1 (01) :134-138
[3]   Detection and differentiation of normal, cancerous, and metastatic cells using nanoparticle-polymer sensor arrays [J].
Bajaj, Avinash ;
Miranda, Oscar R. ;
Kim, Ik-Bum ;
Phillips, Ronnie L. ;
Jerry, D. Joseph ;
Bunz, Uwe H. F. ;
Rotello, Vincent M. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (27) :10912-10916
[4]  
Bharali DJ, 2005, P NATL ACAD SCI USA, V102, P11539, DOI 10.1073/pnas.0504926102
[5]   Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity [J].
Boisselier, Elodie ;
Astruc, Didier .
CHEMICAL SOCIETY REVIEWS, 2009, 38 (06) :1759-1782
[6]   Understanding the Role of Surface Charges in Cellular Adsorption versus Internalization by Selectively Removing Gold Nanoparticles on the Cell Surface with a I2/KI Etchant [J].
Cho, Eun Chul ;
Xie, Jingwei ;
Wurm, Patricia A. ;
Xia, Younan .
NANO LETTERS, 2009, 9 (03) :1080-1084
[7]   Targeting kidney mesangium by nanoparticles of defined size [J].
Choi, Chung Hang J. ;
Zuckerman, Jonathan E. ;
Webster, Paul ;
Davis, Mark E. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (16) :6656-6661
[8]   Mechanism of active targeting in solid tumors with transferrin-containing gold nanoparticles [J].
Choi, Chung Hang J. ;
Alabi, Christopher A. ;
Webster, Paul ;
Davis, Mark E. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (03) :1235-1240
[9]   Strategies for the intracellular delivery of nanoparticles [J].
Chou, Leo Y. T. ;
Ming, Kevin ;
Chan, Warren C. W. .
CHEMICAL SOCIETY REVIEWS, 2011, 40 (01) :233-245
[10]   Gold nanoparticles: Assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology [J].
Daniel, MC ;
Astruc, D .
CHEMICAL REVIEWS, 2004, 104 (01) :293-346
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