Surface functionalization of nanoparticles for nanomedicine

被引:598
作者
Mout, Rubul [1 ]
Moyano, Daniel F. [1 ]
Rana, Subinoy [1 ]
Rotello, Vincent M. [1 ]
机构
[1] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA
基金
美国国家卫生研究院;
关键词
MODIFIED SILICA NANOPARTICLES; MAGNETIC-RESONANCE DETECTION; GOLD NANOPARTICLES; IN-VIVO; COLORIMETRIC DETECTION; OPTICAL-PROPERTIES; CELL-SURFACE; NANO-FLARES; CANCER; DNA;
D O I
10.1039/c2cs15294k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Control of interactions between nanoparticles and biosystems is essential for the effective utilization of these materials in biomedicine. A wide variety of nanoparticle surface structures have been developed for imaging, sensing, and delivery applications. In this research Highlight, we will emphasize advances in tailoring nanoparticle interfaces for implementation in nanomedicine.
引用
收藏
页码:2539 / 2544
页数:6
相关论文
共 60 条
  • [1] Organization of 'nanocrystal molecules' using DNA
    Alivisatos, AP
    Johnsson, KP
    Peng, XG
    Wilson, TE
    Loweth, CJ
    Bruchez, MP
    Schultz, PG
    [J]. NATURE, 1996, 382 (6592) : 609 - 611
  • [2] Cell surface-based differentiation of cell types and cancer states using a gold nanoparticle-GFP based sensing array
    Bajaj, Avinash
    Rana, Subinoy
    Miranda, Oscar R.
    Yawe, Joseph C.
    Jerry, D. Joseph
    Bunz, Uwe H. F.
    Rotello, Vincent M.
    [J]. CHEMICAL SCIENCE, 2010, 1 (01) : 134 - 138
  • [3] Detection and differentiation of normal, cancerous, and metastatic cells using nanoparticle-polymer sensor arrays
    Bajaj, Avinash
    Miranda, Oscar R.
    Kim, Ik-Bum
    Phillips, Ronnie L.
    Jerry, D. Joseph
    Bunz, Uwe H. F.
    Rotello, Vincent M.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (27) : 10912 - 10916
  • [4] Bharali DJ, 2005, P NATL ACAD SCI USA, V102, P11539, DOI 10.1073/pnas.0504926102
  • [5] Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity
    Boisselier, Elodie
    Astruc, Didier
    [J]. CHEMICAL SOCIETY REVIEWS, 2009, 38 (06) : 1759 - 1782
  • [6] Understanding the Role of Surface Charges in Cellular Adsorption versus Internalization by Selectively Removing Gold Nanoparticles on the Cell Surface with a I2/KI Etchant
    Cho, Eun Chul
    Xie, Jingwei
    Wurm, Patricia A.
    Xia, Younan
    [J]. NANO LETTERS, 2009, 9 (03) : 1080 - 1084
  • [7] Targeting kidney mesangium by nanoparticles of defined size
    Choi, Chung Hang J.
    Zuckerman, Jonathan E.
    Webster, Paul
    Davis, Mark E.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (16) : 6656 - 6661
  • [8] Mechanism of active targeting in solid tumors with transferrin-containing gold nanoparticles
    Choi, Chung Hang J.
    Alabi, Christopher A.
    Webster, Paul
    Davis, Mark E.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (03) : 1235 - 1240
  • [9] Strategies for the intracellular delivery of nanoparticles
    Chou, Leo Y. T.
    Ming, Kevin
    Chan, Warren C. W.
    [J]. CHEMICAL SOCIETY REVIEWS, 2011, 40 (01) : 233 - 245
  • [10] Gold nanoparticles: Assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology
    Daniel, MC
    Astruc, D
    [J]. CHEMICAL REVIEWS, 2004, 104 (01) : 293 - 346