Progress in research of GDNF family and their multicomponent receptors.

被引：0

作者：

Dong, M ^{[1
]}

Hu, B ^{[1
]}

机构：

[1] Univ Sci & Technol China, Sch Life Sci, Hefei 230027, Peoples R China

来源：

PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS | 1999年 / 26卷 / 04期

关键词：

neurotrophic factors; GDNF; rat; multicomponent receptors;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Glial cell-line-derived neurtrophic factor (GDNF), neurturin (NTN) and persephin (PSP) define a new family of neurotrophic factors which are distant members of the transforming growth factor-beta (TGF-beta) superfamily and play widely physiological roles in vivo. Recent studies have revealed the existence of a novel family of multicomponent receptors for GDNF family, composed of distinct glycosyl-phosphatidylinositol (GPI)-linked cell surface proteins and a shared transmembrane tyrosine kinase receptor, Ret.

引用

页码：331 / 334

页数：4

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