Estimated daily quercetin intake and association with the prevalence of type 2 diabetes mellitus in Chinese adults

被引：97

作者：

Yao, Zhanxin ^{[1
,2
,3
]}

Gu, Yeqing ^{[2
,3
]}

Zhang, Qing ^{[4
]}

Liu, Li ^{[4
]}

Meng, Ge ^{[2
,3
]}

Wu, Hongmei ^{[2
,3
]}

Xia, Yang ^{[2
,3
]}

Bao, Xue ^{[2
,3
]}

Shi, Hongbin ^{[4
]}

Sun, Shaomei ^{[4
]}

Wang, Xing ^{[4
]}

Zhou, Ming ^{[4
]}

Jia, Qiyu ^{[4
]}

Wu, Yuntang ^{[2
,3
]}

Song, Kun ^{[4
]}

Gao, Weina ^{[1
]}

Guo, Changjiang ^{[1
]}

Niu, Kaijun ^{[2
,3
]}

机构：

[1] Tianjin Inst Hlth & Environm Med, Dept Nutr, 1 Dali Rd, Tianjin 300050, Peoples R China

[2] Tianjin Med Univ, Nutr Epidemiol Inst, 22 Qixiangtai Rd, Tianjin 300070, Peoples R China

[3] Tianjin Med Univ, Sch Publ Hlth, 22 Qixiangtai Rd, Tianjin 300070, Peoples R China

[4] Tianjin Med Univ Gen Hosp, Hlth Management Ctr, Tianjin 300050, Peoples R China

来源：

EUROPEAN JOURNAL OF NUTRITION | 2019年 / 58卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Quercetin; Type 2 diabetes mellitus; Chinese population; Cross-sectional study; NUTRITION EXAMINATION SURVEY; FLAVONOID INTAKE; NATIONAL-HEALTH; RISK; INFLAMMATION; DISEASE; CANCER; WOMEN; HEMOGLOBIN; PROTECTION;

D O I：

10.1007/s00394-018-1713-2

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

PurposeQuercetin is one of potential antidiabetic substances because of its powerful antioxidant and anti-inflammatory actions. The purpose of this study is to estimate daily quercetin intake and assess the relationship between dietary quercetin intake and the prevalence of type 2 diabetes mellitus (T2DM) in a Chinese population.MethodsDietary intake was investigated by a validated 100-item food frequency questionnaire. Daily intakes of quercetin and nutrients were calculated accordingly. T2DM was diagnosed based on the criteria of the American Diabetes Association. Adjusted logistic regression models were used to analyze the relationship between the quartiles of quercetin intake and the prevalence of T2DM.ResultsThe prevalences of T2DM were 8.35% in men and 4.68% in women. The main food sources of quercetin were apple, orange, and green tea. Daily intake of quercetin was 20.92.32mg/day (mean +/- SD). After adjusting for potentially confounding factors, the odds ratios (95% CI) for T2DM across the ascending quartiles of quercetin intake were: 1.00 (reference), 0.75 (0.60-0.95), 0.76 (0.59-0.99), and 0.63 (0.51-0.94).ConclusionsThe results of the present study showed that quercetin intake was inversely related to the prevalence of T2DM in the Chinese population, suggesting a protective effect of quercetin in the development of T2DM.

引用

页码：819 / 830

页数：12

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