The frequent shift to intermediate flora in preterm delivery cases after abnormal vaginal flora screening

被引：9

作者：

Honda, Hiroshi ^{[1
]}

Yokoyama, Takanori ^{[1
]}

Akimoto, Yumiko ^{[1
]}

Tanimoto, Hirotoshi ^{[1
]}

Teramoto, Mitsue ^{[1
]}

Teramoto, Hideki ^{[1
]}

机构：

[1] Hiroshima City Asa Hosp, Dept Obstet & Gynecol, Hiroshima, Japan

来源：

SCIENTIFIC REPORTS | 2014年 / 4卷

关键词：

BACTERIAL VAGINOSIS; LATE MISCARRIAGE; EARLY-PREGNANCY; BIRTH; CLINDAMYCIN; WOMEN; RISK;

D O I：

10.1038/srep04799

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The effect of screening and treatment for abnormal vaginal flora on the reduction of preterm deliveries remains controversial. We evaluated whether this screening and treatment reduces the preterm delivery rate for general-population pregnant women. Pregnant women of the Intervention group (n = 574) underwent the screening test and the treatment of vaginal metronidazole during the early second trimester, and those of the Control group (n = 1,161) did not. We compared the preterm delivery rate between these two groups. We also compared the profiles of vaginal flora of the preterm delivery cases with those of the pregnant women with a normal course. There was no significant difference in the preterm delivery rate between these two groups. However, in the preterm delivery cases, a frequent shift to intermediate flora was observed not before but after the screening in the Intervention group. This shift may explain why most of the previous studies failed in regard to the prevention of preterm deliveries.

引用

页数：5

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