Ductal Carcinoma In Situ: Morphology-Based Knowledge and Molecular Advances

被引：8
作者：
Ross, Dara S. [1 ]
Wen, Yong Hannah [1 ]
Brogi, Edi [1 ]
机构：
[1] Mem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY 10065 USA
来源：
ADVANCES IN ANATOMIC PATHOLOGY | 2013年 / 20卷 / 04期
关键词：
breast; invasive carcinoma; intrinsic subtypes; INVASIVE BREAST-CANCER; BASAL-LIKE SUBTYPE; COMPARATIVE GENOMIC HYBRIDIZATION; PAPILLARY CARCINOMA; LOCAL RECURRENCE; MARGIN WIDTH; EXPRESSION; PROGRESSION; WOMEN; TUMOR;
D O I：
10.1097/PAP.0b013e3182976ed5
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Ductal carcinoma in situ (DCIS) is an established precursor of invasive breast carcinoma. Immunoperoxidase stains for selected markers can assist pathologists in the diagnosis of challenging ductal epithelial proliferations, but they cannot replace morphologic evaluation as the primary and critical assessment of this disease. Molecular studies provide further insight into how DCIS progresses to invasive carcinoma and also confirm the heterogeneity of this lesion. Morphology-based knowledge, immunohistochemistry, and molecular advances in DCIS are the subjects of this review.
引用
收藏
页码：205 / 216
页数：12
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