Antioxidant and Antibacterial Activities of Silver Nanoparticles Biosynthesized by Moringa oleifera through Response Surface Methodology

被引：31

作者：

Mohammed, A. B. Abeer ^{[1
]}

Mohamed, Amr ^{[1
]}

El-Naggar, Noura El-Ahmady ^{[2
]}

Mahrous, Hoda ^{[3
]}

Nasr, Ghada M. ^{[4
]}

Abdella, Asmaa ^{[3
]}

Ahmed, Rasha H. ^{[5
]}

Irmak, Sibel ^{[6
]}

Elsayed, Mohamed S. A. ^{[7
]}

Selim, Samy ^{[8
]}

Elkelish, Amr ^{[9
]}

Alkhalifah, Dalal Hussien M. ^{[10
]}

Hozzein, Wael N. ^{[11
]}

Ali, Abdallah S. ^{[5
]}

机构：

[1] Univ Sadat City, Genet Engn & Biotechnol Res Inst, Dept Microbial Biotechnol, Sadat City, Egypt

[2] City Sci Res & Technol Applicat SRTA City, Genet Engn & Biotechnol Res Inst, Dept Bioproc Dev, Alexandria 21934, Egypt

[3] Univ Sadat City, Genet Engn & Biotechnol Res Inst, Dept Ind Biotechnol, Sadat City, Egypt

[4] Univ Sadat City, Genet Engn & Biotechnol Res Inst, Dept Mol Diagnost, Sadat City, Egypt

[5] Cairo Univ, Dept Microbiol, Fac Agr, Giza 12613, Egypt

[6] Penn State Univ, Dept Agr & Biol Engn, University Pk, PA 16802 USA

[7] Univ Sadat City, Dept Bacteriol Mycol & Immunol, Fac Vet Med, Menoufia 32897, Egypt

[8] Jouf Univ, Dept Clin Lab Sci, Coll Appl Med Sci, Sakaka 72388, Saudi Arabia

[9] Suez Canal Univ, Dept Bot, Fac Sci, Ismailia, Egypt

[10] Princess Nourah Bint Abdulrahman Univ, Dept Biol, Coll Sci, POB 84428, Riyadh 11671, Saudi Arabia

[11] Beni Suef Univ, Bot & Microbiol Dept, Fac Sci, Bani Suwayf, Egypt

来源：

JOURNAL OF NANOMATERIALS | 2022年 / 2022卷

关键词：

GREEN SYNTHESIS; LEAF EXTRACT; ESCHERICHIA-COLI; OPTIMIZATION; FABRICATION; PARTICLES; LEAVES;

D O I：

10.1155/2022/9984308

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

The research highlights the environmentally sustainable biosynthesis of silver nanoparticles from fresh leaves of the herbal medicinal plant Moringa oleifera. They may have been used as anti-inflammatory, anticancer, and antimicrobial agents. M. oleifera extract both reduces and stabilizes silver nanoparticles (AgNPs). Optimum factors needed for AgNP biosynthesis were studied using a central composite design (CCD) matrix. Ultraviolet-visible (UV-Vis) absorption spectroscopy, transmission electron microscopy, and Fourier-transform infrared spectroscopy were used to confirm and characterize the synthesized AgNPs. The biogenic AgNPs demonstrated substantial antibacterial potential against the pathogenic strains Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, and Bacillus subtilis. The antioxidant activity of biosynthesized AgNPs with M. oleifera extract increased from 11.96% when the concentration of the extract was 4 mg/mL to 63.79% at a plant concentration of 20 mg/mL. This research provides an easy and cost-effective technique for the production of stable nanoparticles, with an evaluation of their bioactivity.

引用

页数：15

共 81 条

[41] Novel microbial route to synthesize ZnO nanoparticles using Aeromonas hydrophila and their activity against pathogenic bacteria and fungi [J].