Identification and stereochemistry of the product of 4-HPPD catalyzed oxidation of the ketoacid of methionine

被引：9

作者：

Adlington, RM

Baldwin, JE

Crouch, NP

Lee, MH

MacKinnon, CH

机构：

[1] DYSON PERRINS LAB,OXFORD OX1 3QY,ENGLAND

[2] OXFORD CTR MOL SCI,OXFORD OX1 3QY,ENGLAND

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 16期

关键词：

D O I：

10.1016/0960-894X(96)00362-9

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

4-Hydroxyphenylpyruvate dioxygenase catalyzes the conversion of 2-oxo-5-thiahexanoic acid 1, the ketoacid from methionine (Scheme 1) to an unequal mixture of 4-thiapentanoic acid-4-oxide enantiomers 2a. Copyright (C) 1996 Elsevier Science Ltd.

引用

页码：2003 / 2006

页数：4

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