Two New Cholic Acid Derivatives from the Marine Ascidian-Associated Bacterium Hasllibacter halocynthiae

被引：8

作者：

Kim, Sung Hun ^{[1
,2
]}

Shin, Yun Kyung ^{[3
]}

Sohn, Young Chang ^{[2
]}

Kwon, Hak Cheol ^{[1
]}

机构：

[1] Korea Inst Sci & Technol, Nat Med Ctr, Kangnung 210340, South Korea

[2] Gangneung Wonju Natl Univ, Div Appl Marine Biotechnol & Engn, Fac Marine Biosci & Technol, Kangnung 210702, South Korea

[3] Natl Fisheries Res & Dev Inst, Aquaculture Management Div, Pusan 619705, South Korea

来源：

MOLECULES | 2012年 / 17卷 / 10期

关键词：

Hasllibacter halocynthiae; cholic acids; cholanic acid ketal; marine ascidian; BILE-ACIDS; SP NOV; ROSEOBACTER CLADE; RORETZI; ANTIBACTERIAL; ALKENES;

D O I：

10.3390/molecules171012357

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The investigation of secondary metabolites in liquid cultures of a recently discovered marine bacterium, Hasllibacter halocynthiae strain KME 002(T), led to the isolation of two new cholic acid derivatives. The structures of these compounds were determined to be 3,3,12-trihydroxy-7-ketocholanic acid (1) and 3,3,12-trihydroxy-7-deoxycholanic acid (2) through HRFABMS and NMR data analyses.

引用

页码：12357 / 12364

页数：8

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