Bisphosphonate Therapy and Atypical Fractures

被引：31
作者：
Saleh, Anas [1 ]
Hegde, Vishal V. [2 ]
Potty, Anish G. [1 ]
Lane, Joseph M. [1 ]
机构：
[1] Hosp Special Surg, Dept Orthopaed Surg, New York, NY 10021 USA
[2] Cornell Univ, Weill Cornell Med Coll, New York, NY 10021 USA
来源：
ORTHOPEDIC CLINICS OF NORTH AMERICA | 2013年 / 44卷 / 02期
关键词：
Bisphosphonate therapy; Atypical fractures; Osteoporosis; Atypical femoral fractures; SUPPRESSED BONE TURNOVER; FEMORAL-SHAFT FRACTURES; NITROGEN-CONTAINING BISPHOSPHONATES; SUBTROCHANTERIC STRESS-FRACTURES; DIAPHYSEAL FEMUR FRACTURES; VITAMIN-D SUPPLEMENTATION; POSTMENOPAUSAL WOMEN; PARATHYROID-HORMONE; CORTICAL BONE; MICRODAMAGE ACCUMULATION;
D O I：
10.1016/j.ocl.2013.01.001
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
Atypical femoral fractures have attracted a great deal of attention and controversy in the osteoporosis community because of their association with prolonged bisphosphonate therapy. The purpose of this article is to review the epidemiologic evidence linking bisphosphonates to atypical fractures and to highlight the potential pathologic mechanisms involved in such fractures. A management plan is provided based on the available evidence.
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收藏
页码：137 / +
页数：16
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