Cardiac magnetic resonance appearance of myocarditis caused by high dose IL-2: Similarities to community-acquired myocarditis

被引：20

作者：

Ingkanisorn, WP

Paterson, DI

Calvo, KR

Rosing, DR

Schwartzentruber, DJ

Fuisz, AR

Arai, AE

机构：

[1] NHLBI, Cardiac Energet Lab, NIH, US Dept HHS, Bethesda, MD 20892 USA

[2] Washington Hosp Ctr, Washington, DC 20010 USA

[3] NCI, NIH, US Dept HHS, Bethesda, MD 20892 USA

来源：

JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE | 2006年 / 8卷 / 02期

关键词：

myocarditis; magnetic resonance imaging; interleukin-2; gadolinium; troponin;

D O I：

10.1080/10976640500452000

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The purposecv of this study was to describe and compare the cardiac magnetic resonance (CMR) characteristics of myocarditis caused by high dose interleukin-2 (7 patients) with community-acquired myocarditis (14 patients). A total of 21 patients with suspected myocarditis and elevated cardiac enzymes underwent cine CMR followed by delayed enhancement. The mean ejection fraction was mildly decreased in both groups. The location, pattern, and extent of DE were similar in both groups of patients. The CMR similarities between these two populations suggest that cytokine-mediated cytotoxicity may play an important role in community-acquired myocarditis.

引用

页码：353 / 360

页数：8

共 26 条

[1]

ARETZ HT, 1987, HUM PATHOL, V18, P619

[2]

ATY HA, 2005, J AM COLL CARDIOL, V45, P1815

[3] Detection of viruses in myocardial tissues by polymerase chain reaction: Evidence of adenovirus as a common cause of myocarditis in children and adults [J].