Joining the Dots Between Omics and Environmental Management

被引:18
作者
Leung, Kenneth M. Y. [1 ,2 ,3 ]
机构
[1] Univ Hong Kong, Sch Biol Sci, Pokfulam, Hong Kong, Peoples R China
[2] Univ Hong Kong, Swire Inst Marine Sci, Pokfulam, Hong Kong, Peoples R China
[3] City Univ Hong Kong, State Key Lab Marine Pollut, Kowloon, Hong Kong, Peoples R China
关键词
Genomics; Transcriptomics; Proteomics; Metabolomics; Omics; SPECIES SENSITIVITY DISTRIBUTIONS; SEDIMENT QUALITY GUIDELINES; ADVERSE OUTCOME PATHWAYS; FRAMEWORK;
D O I
10.1002/ieam.2007
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
With the rapid advancement of DNA sequencing technologies and the substantial reduction of their running costs, environmental genomics and transcriptomics become more affordable and popular in environmental toxicology. In parallel, there are also speedy improvements of mass spectrometry and nuclear magnetic resonance spectrometry, enabling high-throughput analyses of proteins and metabolites in biological samples and promoting research studies in proteomics and metabolomics. By applying these high-throughput omics technologies, researchers can quickly generate an unprecedentedly vast amount of biological data that may be useful to environmental management. However, the current pace of applying omics information in environmental management is still very slow, and lags well behind the rapid development of omics-based research. This timely commentary, therefore, calls for joint efforts to increase this pace and join the dots between omics and environmental management, turning omics into practical tools. Herein, I explore how omics can contribute to risk assessment and management of chemicals, and recommend what we can do to facilitate and promote the use of omics information in environmental management. This article is especially dedicated to my role model, mentor, and friend, Peter M Chapman (1951-2017), who sadly passed away on 26 September 2017. (C) 2017 SETAC
引用
收藏
页码:169 / 173
页数:5
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