The hare (Lepus granatensis) as potential sylvatic reservoir of Leishmania infantum in Spain

被引：192

作者：

Molina, R. ^{[1
]}

Jimenez, M. I. ^{[1
]}

Cruz, I. ^{[1
]}

Iriso, A. ^{[2
]}

Martin-Martin, I. ^{[1
]}

Sevillano, O. ^{[2
]}

Melero, S. ^{[3
]}

Bernal, J. ^{[2
]}

机构：

[1] Inst Salud Carlos III, Ctr Nacl Microbiol, Serv Parasitol, Madrid 28220, Spain

[2] Comunidad Autonoma Madrid, Direcc Gen Medio Ambiente, Madrid, Spain

[3] Leganes Council, Madrid, Spain

来源：

VETERINARY PARASITOLOGY | 2012年 / 190卷 / 1-2期

关键词：

Phlebotomus perniciosus; Leishmania infantum; Lepus granatensis; Xenodiagnosis; Sylvatic cycles; Wild reservoir; VISCERAL LEISHMANIASIS; CANINE LEISHMANIASIS; FOX;

D O I：

10.1016/j.vetpar.2012.05.006

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Xenodiagnosis of Leishmania infection in hares (Lepus granatensis) from a focus of human leishmaniasis in Fuenlabrada at southwestern Madrid region (Spain) proved that they are infective to Phlebotomus perniciosus. Molecular characterization of isolates obtained from sand flies infected after xenodiagnosis demonstrates that hares were infected by Leishmania infantum. This is the first evidence of the transmission of L infantum from hares to sand flies. Moreover the results confirm the role that these animals can play as wild reservoirs of leishmaniasis for the recent outbreak of visceral leishmaniasis in Madrid. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：268 / 271

页数：4

共 21 条

[1] KALA-AZAR IN PORTUGAL .4. THE WILD RESERVOIR - THE ISOLATION OF A LEISHMANIA FROM A FOX [J].

ABRANCHES, P ;

SILVA, FMC ;

RIBEIRO, MMS ;

LOPES, FJ ;

GOMES, LT .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1983, 77 (03) :420-421

[2] Emergence of visceral leishmaniasis in central Israel [J].

Baneth, G ;

Dank, G ;

Keren-Kornblatt, E ;

Sekeles, E ;

Adini, I ;

Eisenberger, CL ;

Schnur, LF ;

King, R ;

Jaffe, CL .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1998, 59 (05) :722-725

[3] ISOLATION OF LEISHMANIA STRAINS FROM RATTUS-RATTUS IN ITALY [J].

BETTINI, S ;

GRADONI, L ;

POZIO, E .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1978, 72 (04) :441-442

[4] Cryptic Leishmaniosis by Leishmania infantum, a feature of canines only? A study of natural infection in wild rabbits, humans and dogs in southeastern Spain [J].

Chitimia, L. ;

Munoz-Garcia, C. I. ;

Sanchez-Velasco, D. ;

Lizana, V. ;

del Rio, L. ;

Murcia, L. ;

Fisa, R. ;

Riera, C. ;

Gimenez-Font, P. ;

Jimenez-Montalban, P. ;

Martinez-Ramirez, A. ;

Meseguer-Meseguer, J. M. ;

Garcia-Bacete, I. ;

Sanchez-Isarria, M. A. ;

Sanchis-Monsonis, G. ;

Garcia-Martinez, J. D. ;

Vicente, V. ;

Segovia, M. ;

Berriatua, E. .

VETERINARY PARASITOLOGY, 2011, 181 (01) :12-16

[5] A parasitological survey of wild red foxes (Vulpes vulpes) from the province of Guadalajara, Spain [J].

Criado-Fornelio, A ;

Gutierrez-Garcia, L ;

Rodriguez-Caabeiro, F ;

Reus-Garcia, E ;

Roldan-Soriano, MA ;

Diaz-Sanchez, MA .

VETERINARY PARASITOLOGY, 2000, 92 (04) :245-251

[6] Epidemiology of canine leishmaniosis in Catalonia (Spain) -: The example of the Priorat focus [J].

Fisa, R ;

Gállego, M ;

Castillejo, S ;

Aisa, MJ ;

Serra, T ;

Riera, C ;

Carrió, J ;

Gállego, J ;

Portús, M .

VETERINARY PARASITOLOGY, 1999, 83 (02) :87-97

[7] Phylogeny of Leishmania species based on the heat-shock protein 70 gene [J].

Fraga, Jorge ;

Margarita Montalvo, Ana ;

De Doncker, Simonne ;

Dujardin, Jean-Claude ;

Van der Auwera, Gert .

INFECTION GENETICS AND EVOLUTION, 2010, 10 (02) :238-245

[8] Antibodies against Lutzomyia longipalpis saliva in the fox Cerdocyon thous and the sylvatic cycle of Leishmania chagasi [J].

Gomes, Regis B. ;

Mendonca, Ivete L. ;

Silva, Vladimir C. ;

Ruas, Jeronimo ;

Silva, Mauro B. ;

Cruz, Maria S. P. ;

Barral, Aldina ;

Costa, Carlos H. N. .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2007, 101 (02) :127-133

[9] Urban parasitology: visceral leishmaniasis in Brazil [J].

Harhay, Michael O. ;

Olliaro, Piero L. ;

Costa, Dorcas Lamounier ;

Nery Costa, Carlos Henrique .

TRENDS IN PARASITOLOGY, 2011, 27 (09) :403-409

[10] Analysis of ribosomal DNA internal transcribed spacer sequences of the Leishmania donovani complex [J].

Kuhls, K ;

Mauricio, IL ;

Pratlong, F ;

Presber, W ;

Schönian, G .

MICROBES AND INFECTION, 2005, 7 (11-12) :1224-1234

← 1 2 3 →