New color chemosensors for monosaccharides based on Azo dyes

被引:131
作者
DiCesare, N [1 ]
Lakowicz, JR [1 ]
机构
[1] Univ Maryland, Sch Med, Ctr Fluorescence Spect, Baltimore, MD 21201 USA
关键词
D O I
10.1021/ol016813p
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] Sugar detection is important for many applications. New developments in 7 sugar signaling would provide new technologies to monitor glucose and other sugars. Azo dye 1 presents a new way to build molecular color sensors for monosaccharides. The boronic acid group is used as chelator group for monosaccharides and linked directly,in resonance with the aromatic dye. Dye 1 shows a color change, from orange to purple, in the presence of sugar at neutral pH.
引用
收藏
页码:3891 / 3893
页数:3
相关论文
共 11 条
[1]   Simple and rapid visual sensing of saccharides [J].
Davis, CJ ;
Lewis, PT ;
McCarroll, ME ;
Read, MW ;
Cueto, R ;
Strongin, RM .
ORGANIC LETTERS, 1999, 1 (02) :331-334
[2]   Spectral properties of fluorophores combining the boronic acid group with electron donor or withdrawing groups. Implication in the development of fluorescence probes for saccharides [J].
DiCesare, N ;
Lakowicz, JR .
JOURNAL OF PHYSICAL CHEMISTRY A, 2001, 105 (28) :6834-6840
[3]   DEVELOPMENT OF THE IMPLANTABLE GLUCOSE SENSOR - WHAT ARE THE PROSPECTS AND WHY IS IT TAKING SO LONG [J].
GOUGH, DA ;
ARMOUR, JC .
DIABETES, 1995, 44 (09) :1005-1009
[4]   Synthetic receptors [J].
Hartley, JH ;
James, TD ;
Ward, CJ .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 2000, (19) :3155-3184
[5]   Implanted electrochemical glucose sensors for the management of diabetes [J].
Heller, A .
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, 1999, 1 :153-175
[6]   Saccharide sensing with molecular receptors based on boronic acid [J].
James, TD ;
Sandanayake, KRAS ;
Shinkai, S .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1996, 35 (17) :1910-1922
[7]   Colorimetric sugar sensing method useful in "neutral" aqueous media [J].
Koumoto, K ;
Shinkai, S .
CHEMISTRY LETTERS, 2000, (08) :856-857
[8]   POLYOL COMPLEXES AND STRUCTURE OF THE BENZENEBORONATE ION [J].
LORAND, JP ;
EDWARDS, JO .
JOURNAL OF ORGANIC CHEMISTRY, 1959, 24 (06) :769-774
[9]  
Mizuno T., 2000, J CHEM SOC P1, V1, P407
[10]   NOVEL MOLECULAR SENSORS FOR SACCHARIDES BASED ON THE INTERACTION OF BORONIC ACID AND AMINES - SACCHARIDE SENSING IN NEUTRAL WATER [J].
SANDANAYAKE, KRAS ;
SHINKAI, S .
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1994, (09) :1083-1084