Smart sensors/actuators for biomedical applications: Review

被引:52
作者
Ponmozhi, J. [1 ]
Frias, Clara [1 ,2 ]
Marques, Torres [2 ]
Frazao, O. [3 ]
机构
[1] Univ Porto, Inst Engn Mecan & Gestao Ind INEGI, P-4200465 Oporto, Portugal
[2] Univ Porto, FEUP, P-4200465 Oporto, Portugal
[3] INESC Porto, Unidade Optoelect & Sistemas Elect, P-4169007 Oporto, Portugal
关键词
Biosensors; Actuators; MEMS; Smart implants; CNTs; SURFACE-PLASMON RESONANCE; CAPACITIVE PRESSURE SENSOR; CARBON-NANOTUBE; GLUCOSE BIOSENSORS; PASTE ELECTRODE; IN-VITRO; SINGLE; IMMUNOSENSOR; SENSITIVITY; FABRICATION;
D O I
10.1016/j.measurement.2012.02.006
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
This paper reflects on review of smart sensor activities for biomedical applications. The rise of biotechnology has provided innovative development of new therapies and detection methods for life threatening diseases. As a worldwide research focus, there is especially a strong interest in the use of microsystems in health care, particularly as smart implantable devices. Recent years have seen an increasing activity of hip and knee replacement and other type of implants, which are some of the most frequently performed surgical procedures in the world. Loosening of hip prosthesis is the dominant issue for many patients who undergo a hip arthroplasty. Artificial joints are subject to chronic infections associated with bacterial biofilms, which only can be eradicated by the traumatic removal of the implant followed by sustained intravenous antibiotic therapy. This review focuses on the clinical experience using all kinds of smart implants like orthopedic implants instrumented with strain gauges, retina implant system using image sensors. Technical design improvements will enhance function, quality of life, and longevity of total knee arthroplasty and all other kind of implants. Application of biocompatible nanomaterials in implantable biosensors for continuous monitoring of metabolites is an area of sustained scientific and technological interests. Crown Copyright (C) 2012 Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:1675 / 1688
页数:14
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