Screening for Aneuploidy in Multiple Gestations The Challenges and Options

被引：4

作者：

Bender, Whitney ^{[1
]}

Dugoff, Lorraine ^{[2
]}

机构：

[1] Hosp Univ Penn, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA

[2] Univ Penn, Perelman Sch Med, Reprod Genet Div, Maternal Fetal Med & Reprod Genet, 2 Silverstein Bldg,3400 Spruce St, Philadelphia, PA 19104 USA

来源：

OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA | 2018年 / 45卷 / 01期

关键词：

Multiple gestation; Aneuploidy; Nuchal translucency; Serum screening; Cell-free DNA; Noninvasive prenatal testing; COMBINING NUCHAL TRANSLUCENCY; CHORIONIC-GONADOTROPIN LEVELS; FREE DNA ANALYSIS; TWIN PREGNANCIES; DOWN-SYNDROME; MATERNAL PLASMA; PRENATAL-DIAGNOSIS; TRISOMIES; 21; FETAL DNA; TRISOMY-21;

D O I：

10.1016/j.ogc.2017.10.004

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

As the incidence of multiple gestations increases, the need for effective aneuploidy screening grows. There are unique challenges associated with aneuploidy screening in twins, and the data supporting its use are limited. This article summarizes the risk of aneuploidy for twin gestations and the available screening methods, including nuchal translucency, first-trimester and second-trimester serum screening, and cell-free DNA screening.

引用

页码：41 / +

页数：14

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