Evidence for partial pharmaceutical reversal of the cancer anorexia-cachexia syndrome: the case of anamorelin

被引：29

作者：

Anker, Stefan D. ^{[1
]}

Coats, Andrew J. S. ^{[2
,3
]}

Morley, John E. ^{[4
,5
]}

机构：

[1] Univ Med Ctr Gottingen UMG, Dept Cardiol & Pneumol, Div Innovat Clin Trials, Gottingen, Germany

[2] Monash Univ, Melbourne, Vic 3004, Australia

[3] Univ Warwick, Coventry CV4 7AL, W Midlands, England

[4] St Louis Univ, Sch Med, Div Geriatr Med, St Louis, MO 63104 USA

[5] St Louis Univ, Sch Med, Dept Endocrinol, St Louis, MO USA

来源：

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE | 2015年 / 6卷 / 04期

关键词：

SKELETAL-MUSCLE; DOUBLE-BLIND; BODY-COMPOSITION; SARCOPENIA; NUTRITION; CONSENSUS; CAPACITY;

D O I：

10.1002/jcsm.12063

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

A major component of the cancer anorexia-cachexia syndrome is a decline in food intake. Up until now none of the drugs that improve appetite also improve skeletal muscle. Recent studies have suggested that the oral ghrelin-analog, anamorelin, increased food intake and muscle mass. Unfortunately, it does not increase muscle power. Its regulatory future is uncertain, although it has important clinical effects.

引用

页码：275 / 277

页数：3

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