Metabolic Engineering for the Production of Lactic Acid from Xylose by the Thermoanaerobacterium Strain

被引：0

作者：

Yang, Xiaofeng ^{[1
]}

Lai, Chaofeng ^{[1
]}

Yang, Shuai ^{[1
]}

Zhu, Muzi ^{[1
]}

Li, Shuang ^{[1
]}

Wang, Jufang ^{[1
]}

机构：

[1] South China Univ Technol, Sch Biosci & Bioengn, Guangzhou, Guangdong, Peoples R China

来源：

ISBE 2011: 2011 INTERNATIONAL CONFERENCE ON BIOMEDICINE AND ENGINEERING, VOL 3 | 2011年

关键词：

Thermoanaerobacterium; lactic acid; metabolic engineering; xylose; PERSPECTIVES; ETHANOL;

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Conversion of lignocelluloses to lactic acid can reduce the cost of the substrates, while the process requires strains capable of fermenting sugar mixtures of glucose and xylose. The screened strain of Thermoanaerobacterium aotearoense SCUT27 was successfully engineered by deleting the phosphate acetyltransferase and the acetate kinase. The resulting strain can grow on glucose and xylose to produce lactic acid under oxygen limited condition with the 1.3 and 2.5 folds increase of the quantity and yield of lactic acid production, respectively.

引用

页码：9 / 12

页数：4

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