Drug Toxicities of Common Analgesic Medications in the Emergency Department

被引：8

作者：

Ciejka, Mateusz ^{[1
]}

Khoa Nguyen ^{[1
]}

Bluth, Martin H. ^{[2
,3
]}

Dubey, Elizabeth ^{[1
]}

机构：

[1] Wayne State Univ, Sch Med, Dept Emergency Med, 4201 St Antoine,6F UHC, Detroit, MI 48201 USA

[2] Wayne State Univ, Sch Med, Dept Pathol, 540 East Canfield, Detroit, MI 48201 USA

[3] Consolidated Lab Management Syst, 24555 Southfield Rd, Southfield, MI 48075 USA

来源：

CLINICS IN LABORATORY MEDICINE | 2016年 / 36卷 / 04期

关键词：

Toxicity; Acetaminophen; Opioid; Narcotic; Aspirin; Salicylate; Emergency department; N-ACETYLCYSTEINE TREATMENT; ACETAMINOPHEN OVERDOSE; ACTIVATED-CHARCOAL; HEPATOTOXICITY; NALOXONE; PARKINSONISM; MANAGEMENT; INGESTION; MECHANISM; MORPHINE;

D O I：

10.1016/j.cll.2016.07.003

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

About 75% of patients present to the emergency department with a complaint of pain. There are multiple prescribed and over-the-counter medications that are available for the treatment of pain. Acetaminophen, opioids, and aspirin are commonly used agents that are available as single agents or in combination with other medications. However, all of these agents are susceptible to toxic overdose, which requires prompt recognition through clinical and laboratory assessment modalities and initiation of therapy to reduce the risk of morbidity and mortality.

引用

页码：761 / +

页数：17

共 76 条

[61] ACETAMINOPHEN OVERDOSE - A 48-HOUR INTRAVENOUS N-ACETYLCYSTEINE TREATMENT PROTOCOL [J].

SMILKSTEIN, MJ ;

BRONSTEIN, AC ;

LINDEN, C ;

AUGENSTEIN, WL ;

KULIG, KW ;

RUMACK, BH .

ANNALS OF EMERGENCY MEDICINE, 1991, 20 (10) :1058-1063

[62]

Smith H S., 2009, Current Therapy in Pain

[63] Opioid-induced nausea and vomiting [J].

Smith, Howard S. ;

Smith, Joshua M. ;

Seidner, Pya .

ANNALS OF PALLIATIVE MEDICINE, 2012, 1 (02) :121-129

[64]

Smith HS, 2009, MAYO CLIN PROC, V84, P613, DOI 10.1016/S0025-6196(11)60750-7

[65]

Standridge JB, 2010, AM FAM PHYSICIAN, V81, P635

[66]

Tanabe P, 1999, J Emerg Nurs, V25, P171, DOI 10.1016/S0099-1767(99)70200-X

[67] Position paper update: Whole bowel irrigation for gastrointestinal decontamination of overdose patients [J].

Thanacoody, Ruben ;

Caravati, E. Martin ;

Troutman, Bill ;

Hojer, Jonas ;

Benson, Blaine ;

Hoppu, Kalle ;

Erdman, Andrew ;

Bedry, Regis ;

Megarbane, Bruno .

CLINICAL TOXICOLOGY, 2015, 53 (01) :5-12

[68] Body packing - The internal concealment of illicit drugs [J].

Traub, SJ ;

Hoffman, RS ;

Nelson, LS .

NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (26) :2519-2526

[69]

Trost LC, 1996, J PHARMACOL EXP THER, V278, P1000

[70] Opioid receptors [J].

Waldhoer, M ;

Bartlett, SE ;

Whistler, JL .

ANNUAL REVIEW OF BIOCHEMISTRY, 2004, 73 :953-990

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