Drug Toxicities of Common Analgesic Medications in the Emergency Department

被引:8
作者
Ciejka, Mateusz [1 ]
Khoa Nguyen [1 ]
Bluth, Martin H. [2 ,3 ]
Dubey, Elizabeth [1 ]
机构
[1] Wayne State Univ, Sch Med, Dept Emergency Med, 4201 St Antoine,6F UHC, Detroit, MI 48201 USA
[2] Wayne State Univ, Sch Med, Dept Pathol, 540 East Canfield, Detroit, MI 48201 USA
[3] Consolidated Lab Management Syst, 24555 Southfield Rd, Southfield, MI 48075 USA
关键词
Toxicity; Acetaminophen; Opioid; Narcotic; Aspirin; Salicylate; Emergency department; N-ACETYLCYSTEINE TREATMENT; ACETAMINOPHEN OVERDOSE; ACTIVATED-CHARCOAL; HEPATOTOXICITY; NALOXONE; PARKINSONISM; MANAGEMENT; INGESTION; MECHANISM; MORPHINE;
D O I
10.1016/j.cll.2016.07.003
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
About 75% of patients present to the emergency department with a complaint of pain. There are multiple prescribed and over-the-counter medications that are available for the treatment of pain. Acetaminophen, opioids, and aspirin are commonly used agents that are available as single agents or in combination with other medications. However, all of these agents are susceptible to toxic overdose, which requires prompt recognition through clinical and laboratory assessment modalities and initiation of therapy to reduce the risk of morbidity and mortality.
引用
收藏
页码:761 / +
页数:17
相关论文
共 76 条
[1]   LIVER TOXICITY AFTER ACETAMINOPHEN INGESTION INADEQUACY OF DOSE ESTIMATE AS AN INDEX OF RISK [J].
AMBRE, J ;
ALEXANDER, M .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1977, 238 (06) :500-501
[2]   Position paper: Whole bowel irrigation [J].
Seger D. ;
Meulenbelt J. .
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY, 2004, 42 (06) :843-854
[3]  
[Anonymous], SAL SALY THER DRUG M
[4]  
[Anonymous], 2015, MILLERSS ANESTHESIA
[5]  
[Anonymous], PERIOPERATIVE PAIN M
[6]  
[Anonymous], CARDIAC PHARM
[7]  
[Anonymous], FAMILY MED PRINCIPLE
[8]  
[Anonymous], PHARM OPIOIDS
[9]  
[Anonymous], 2014, Textbook of Forensic Medicine & Toxicology
[10]  
[Anonymous], AM J EMERG MED