Highly accelerating effect of Lewis acids on ruthenium(II)-catalyzed radical addition reactions

被引：7
|
作者：
Hoshimoto, S [1 ]
Matsunaga, H [1 ]
Wada, M [1 ]
Kunieda, T [1 ]
机构：
[1] Kumamoto Univ, Fac Pharmaceut Sci, Kumamoto 8620973, Japan
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 2002年 / 50卷 / 03期
关键词：
2-oxazolone; radical addition; ruthenium(II) complex; Lewis acid; accelerating effect;
D O I：
10.1248/cpb.50.435
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The intramolecular ruthenium(II)-catalyzed radical addition of the trichloroacetyl pendant group to the 2-oxazolone skeleton is greatly enhanced in the presence of catalytic Lewis acids including rare earth: metal triflates, thus providing a convenient route to a highly potential chiral synthon for vic-amino alcohols.
引用
收藏
页码：435 / 438
页数：4
相关论文
共 50 条
  • [1] Highly selective radical reactions of sulfonyl chlorides catalyzed by a ruthenium(II) complex
    Kamigata, N
    Shimizu, T
    REVIEWS ON HETEROATOM CHEMISTRY, 1997, 17 : 1 - 50
  • [2] HIGHLY SELECTIVE RADICAL REACTIONS CATALYZED BY RUTHENIUM COMPLEX
    KAMIGATA, N
    KAMEYAMA, M
    JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 1989, 47 (05) : 436 - 447
  • [3] Chiral copper(II) complexes as Lewis acids for catalyzed cycloaddition, carbonyl addition, and conjugate addition reactions
    Evans, DA
    Rovis, T
    Johnson, JS
    PURE AND APPLIED CHEMISTRY, 1999, 71 (08) : 1407 - 1415
  • [4] Ruthenium-catalyzed Atom Transfer Radical Addition Reactions
    Severin, Kay
    CHIMIA, 2012, 66 (06) : 386 - 388
  • [5] Highly enantioselective atom-transfer radical cyclization reactions catalyzed by chiral Lewis acids
    Yang, D
    Gu, S
    Yan, YL
    Zhu, NY
    Cheung, KK
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (35) : 8612 - 8613
  • [6] Highly enantioselective atom-transfer radical cyclization reactions catalyzed by chiral Lewis acids.
    Yang, D
    Yan, YL
    Gu, S
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 224 : U231 - U231
  • [7] Addition reactions to alkynes catalyzed by ruthenium complexes
    Tokunaga, M
    Wakatsuki, Y
    JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 2000, 58 (06) : 587 - 596
  • [8] Asymmetric Intramolecular Diels-Alder Reactions of Trienals Catalyzed by Chiral Ruthenium Lewis Acids
    Thamapipol, Sirinporn
    Kuendig, E. Peter
    CHIMIA, 2011, 65 (04) : 268 - 270
  • [9] Use of Lewis acids in free radical reactions
    Renaud, P
    Gerster, M
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1998, 37 (19) : 2563 - 2579
  • [10] Use of Lewis Acids in Free Radical Reactions
    Université de Fribourg, Inst. de Chim. Organique Perolles, CH-1700 Fribourg, Switzerland
    Angew. Chem. Int. Ed., 19 (2562-2579):
12345