Antibacterial activity of dithiothreitol reduced graphene oxide

被引:123
作者
Gurunathan, Sangiliyandi [1 ]
Han, Jae Woong [1 ]
Dayem, Ahmed Abdal [1 ]
Eppakayala, Vasuki [1 ]
Park, Mi-Ryung [1 ]
Kwon, Deug-Nam [1 ]
Kim, Jin-Hoi [1 ]
机构
[1] Konkuk Univ, Dept Anim Biotechnol, Seoul 143701, South Korea
关键词
Graphene oxide; Reduced graphene oxide; Dithiothreitol; E; coli; UV-visible spectroscopy; Raman spectroscopy; OXIDATIVE STRESS; GRAPHITE OXIDE; ESCHERICHIA-COLI; CARBON NANOTUBES; FACILE SYNTHESIS; GREEN REDUCTION; RAMAN-SPECTRA; VITAMIN-C; NANOPARTICLES; INACTIVATION;
D O I
10.1016/j.jiec.2012.12.029
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A green and simple approach is described for the large scale synthesis of reduced graphene oxide (rGO). The transition of graphene oxide (GO) into graphene was confirmed using various analytical techniques. Raman spectroscopy data indicate the partial removal of oxygen-containing functional groups from the surface of GO and formation of graphene. X-ray diffraction (XRD) was used to investigate the crystallinity of graphene nanosheets. The antibacterial activity of GO and rGO was evaluated using cell viability, reactive oxygen species (ROS) production and DNA fragmentation assays. The results suggest that GO and rGO possessed an excellent antimicrobial activity against Escherichia coli. (c) 2012 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:1280 / 1288
页数:9
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