Impact of the Opioid Epidemic

被引：13

作者：

Lavonas, Eric J. ^{[1
,2
]}

Dezfulian, Cameron ^{[3
,4
]}

机构：

[1] Denver Hlth, Dept Emergency Med, Rocky Mt Poison & Drug Safety, 777 Bannock St,MC 0108, Denver, CO 80238 USA

[2] Univ Colorado, Dept Emergency Med, Sch Med, Aurora, CO USA

[3] Univ Pittsburgh, Crit Care Med, Sch Med, 4401 Penn Ave,CHP Fac Pavil,Room 2119, Pittsburgh, PA 15224 USA

[4] Univ Pittsburgh, Clin & Translat Sci, Sch Med, 4401 Penn Ave,CHP Fac Pavil,Room 2119, Pittsburgh, PA 15224 USA

来源：

CRITICAL CARE CLINICS | 2020年 / 36卷 / 04期

关键词：

Opioid analgesics; Overdose; Opioid use disorder; Respiratory arrest; Cardiac arrest; Naloxone; Resuscitation; Critical care; INJECTION-DRUG USE; HEART-ASSOCIATION GUIDELINES; TORSADES-DE-POINTES; GAG REFLEX; UNITED-STATES; CARDIOPULMONARY-RESUSCITATION; INFECTIVE ENDOCARDITIS; EMERGENCY-DEPARTMENT; PULMONARY-EDEMA; NALOXONE;

D O I：

10.1016/j.ccc.2020.07.006

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

In recent years the prescription opioid overdose epidemic has decreased, but has been more than offset by increases in overdose caused by fentanyl and fentanyl analogues. Opioid overdose patients should receive naloxone if they have significant respiratory depression and/or loss of protective airway reflexes. Patients who receive naloxone should be observed for recurrent opioid effects. Patients with opioid overdose may be admitted to the intensive care unit for naloxone infusions, treatment of noncardiogenic pulmonary edema, autonomic instability, or sequelae of hypoxia-ischemia or cardiac arrest. Primary and secondary prevention are important to reduce the number of people with life-threatening opioid overdose. © 2020 Elsevier Inc.

引用

页码：753 / 769

页数：17

共 92 条

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