HAART: a risk factor for development of porphyria cutanea tarda?

被引：6

作者：

Bernardes Filho, Fred ^{[1
]}

Pinto Quaresma Santos, Maria Victoria ^{[1
]}

de Matos Pinto de Carvalho, Felipe Nazareth ^{[1
]}

Carneiro de Castro, Carlos Gustavo ^{[1
]}

Dobao, Elisabete ^{[1
]}

Lyra, Marcelo Rosandiski ^{[3
]}

de Menezes, Vincius ^{[2
]}

da Costa Nery, Jose Augusto ^{[1
,2
]}

机构：

[1] Inst Dermatol Prof Rubem David Azulay, Rio De Janeiro, RJ, Brazil

[2] Fundacao Oswaldo Cruz, Lab Hanseniase, Inst Oswaldo Cruz, Rio De Janeiro, RJ, Brazil

[3] Fundacao Oswaldo Cruz, Inst Pesquisa Clin Evandro Chagas, Rio De Janeiro, RJ, Brazil

来源：

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2012年 / 45卷 / 06期

关键词：

Porphyria cutanea tarda; HAART; HIV; VIRUS-INFECTION;

D O I：

10.1590/S0037-86822012000600022

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Porphyria cutanea tarda (PCT) is caused by inherited or acquired partial deficiency of the uroporphyrinogen-decarboxylase (Uro-D) enzyme activity. It is the most common form of porphyria. The main triggering factors to the development of porphyria cutanea tarda are alcohol, hepatitis C virus and human immunodeficiency virus. There are several reports of PCT associated with drugs, among them, antiretroviral therapy. We describe three HIV-positive patients, which showed photosensitivity as well as the emergence of tense blisters on sun-exposed areas during the use of highly active antiretroviral therapy (HAART) and discuss the possibility of PCT after the use of these drugs by those patients.

引用

页码：764 / 767

页数：4

共 12 条

[1] Associacao Brasileira de Porfiria (ABRAPO), MED PORF
[2] Porphyria cutanea tarda in an HIV-1-infected patient after the initiation of tipranavir/ritonavir: case report
Celesia, Benedetto M.
Onorante, Anna
Nunnari, Giuseppe
Mughini, Maria T.
Mavilla, Sergio
Massimino, Santa D.
Russo, Rosario
[J]. AIDS, 2007, 21 (11) : 1495 - 1496
[3] Associations Among Behavior-Related Susceptibility Factors in Porphyria Cutanea Tarda
Jalil, Sajid
Grady, James J.
Lee, Chul
Anderson, Karl E.
[J]. CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2010, 8 (03) : 297 - 302
[4] Liver Cirrhosis Induced by Porphyria Cutanea Tarda: A Case Report and Review
Lee, Kwang Gyun
Hyun, Jong Jin
Seo, Yeon Seok
Keum, Bora
Yim, Hyung Joon
Jeen, Yoon Tae
Lee, Hong Sik
Chun, Hoon Jai
Kim, Chang Duck
Ryu, Ho Sang
Um, Soon Ho
[J]. GUT AND LIVER, 2010, 4 (04) : 551 - 555
[5] Influence of previous hepatitis B virus infection on liver fibrosis in patients with chronic hepatitis C: a retrospective case series evaluation
Lisboa Neto, Gaspar
Tengan, Fatima Mitiko
Cavalheiro, Norma de Paula
Barone, Antonio Alci
[J]. REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 2010, 43 (04) : 416 - 420
[6] Oliveira Junior JV, 2010, REV BRAS CLIN MED, V8, P286
[7] PORPHYRIA CUTANEA-TARDA IN ASSOCIATION WITH THE HUMAN IMMUNODEFICIENCY VIRUS-INFECTION
ONG, ELC
ELLIS, ME
MCDOWELL, D
GEBRIL, M
WEINKOVE, C
EAD, R
[J]. POSTGRADUATE MEDICAL JOURNAL, 1988, 64 (758) : 956 - 957
[8] ROCAS B, 2001, ANTIVIR THER S, V6, P71
[9] The American Porphyria Foundation (APF), 2010, PORPH CUT TARD
[10] The American Porphyria Foundation (APF), 2010, DRUG DAT SAF UNS DRU

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