Structure and relaxivity of macrocyclic gadolinium complexes incorporating pyridyl and 4-morpholinopyridyl substituents

被引：39

作者：

Aime, S

Batsanov, AS

Botta, M

Howard, JAK

Lowe, MP

Parker, D

机构：

[1] Univ Durham, Dept Chem, Durham DH1 3LE, England

[2] Univ Turin, IFM, Dipartimento Chim, I-10125 Turin, Italy

来源：

NEW JOURNAL OF CHEMISTRY | 1999年 / 23卷 / 07期

关键词：

D O I：

10.1039/a901704f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Octadentate N5O3 ligands containing a coordinating pyridyl group form kinetically stable complexes with Eu and Gd that resist protonation; the structure of a representative Gd complex reveals a short Gd-N-py bond [2.535(1) Angstrom], and the water exchange rate (k(ex)(298) = 2.7 x 10(6) s(-1)) is sufficiently fast so as not to limit the pH independent relaxivity (R-1p(298) = 5.3 mM(-1) s(-1), 20 MHz).

引用

页码：669 / 670

页数：2

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