Recent Advances in the Synthesis of 1-Monosubstituted 1,2,3-Triazoles

被引：18

作者：

Jiang, Yubo ^{[1
]}

Kuang, Chunxiang ^{[2
]}

机构：

[1] Kunming Univ Sci & Technol, Fac Sci, Kunming, Peoples R China

[2] Tongji Univ, Dept Chem, Shanghai, Peoples R China

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2013年 / 13卷 / 05期

基金：

中国国家自然科学基金;

关键词：

Acetylene; 1-monosubstituted; substituted acetylene; 1,2,3-triazole; vinyl compounds; CATALYZED N-ARYLATION; CONVENIENT SYNTHESIS; CLICK CHEMISTRY; 1,3-DIPOLAR CYCLOADDITION; CALCIUM CARBIDE; AZIDES; ACID; FACILE;

D O I：

10.2174/1389557511313050008

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

1-Monosubstituted 1,2,3-triazoles have widespread applications in diverse fields, and their preparation has attracted increasing attention. This review mainly covers the modern advances in the synthesis of these heterocycles based on different methods including the substitution of 1H-1,2,3-triazole and cycloaddition reactions involving moieties, such as acetylene, substituted acetylene, and vinyl compounds, among others.

引用

页码：713 / 719

页数：7

共 47 条

[1]

Bertho A., 1925, EUR J INORG CHEM, V58, P859

[2]

Butora G., 2009, U.S. Patent, Patent No. [7,598,243, 7598243]

[3] Structural studies on bioactive compounds.: Part 36:: Design, synthesis and biological evaluation of pyrimethamine-based antifolates against Pneumocystis carinii [J].

Chan, DCM ;

Laughton, CA ;

Queener, SF ;

Stevens, MFG .

BIOORGANIC & MEDICINAL CHEMISTRY, 2002, 10 (09) :3001-3011

[4] Chemistry strategies in early drug discovery: an overview of recent trends [J].

Colombo, Matteo ;

Peretto, Ilaria .

DRUG DISCOVERY TODAY, 2008, 13 (15-16) :677-684

[5] Monosubstituted 1,2,3-triazoles from two-step one-pot deprotection/click additions of trimethylsilylacetylene [J].

Fletcher, James T. ;

Walz, Sara E. ;

Keeney, Matthew E. .

TETRAHEDRON LETTERS, 2008, 49 (49) :7030-7032

[6] COPPER(I)-CATALYZED DIRECT ARYLATION OF 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES WITH ARYL IODIDES [J].

Fukuzawa, Shin-ichi ;

Shimizu, Eiji ;

Ogata, Kenichi .

HETEROCYCLES, 2009, 78 (03) :645-655

[7] Marrying click chemistry with polymerization: expanding the scope of polymeric materials [J].

Golas, Patricia L. ;

Matyjaszewski, Krzysztof .

CHEMICAL SOCIETY REVIEWS, 2010, 39 (04) :1338-1354

[8] Efficient synthesis of deuterated 1,2,3-triazoles [J].

Gonda, Zsombor ;

Loerincz, Krisztian ;

Novak, Zoltan .

TETRAHEDRON LETTERS, 2010, 51 (48) :6275-6277

[9] Synthesis of an Antibacterial Compound Containing a 1,4-Substituted 1H-1,2,3-Triazole: A Scaleable Alternative to the "Click" Reaction [J].

Hanselmann, Roger ;

Job, Gabriel E. ;

Johnson, Graham ;

Lou, Rongliang ;

Martynow, Jacek G. ;

Reeve, Maxwell M. .

ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2010, 14 (01) :152-158

[10] Microwave Irradiation as an Effective Means of Synthesizing Unsubstituted N-Linked 1,2,3-Triazoles from Vinyl Acetate and Azides [J].

Hansen, Signe Grann ;

Jensen, Henrik Helligso .

SYNLETT, 2009, (20) :3275-3278

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