2D Short-Time Fourier Transform for local morphological analysis of meibomian gland images

被引:5
作者
Ciezar, Kamila [1 ,2 ]
Pochylski, Mikolaj [1 ]
机构
[1] Adam Mickiewicz Univ, Fac Phys, Poznan, Poland
[2] Augenarztpraxen Berlin Suedwest, Berlin, Germany
来源
PLOS ONE | 2022年 / 17卷 / 06期
关键词
INTERNATIONAL WORKSHOP; DYSFUNCTION REPORT; DRY EYE; MEIBOGRAPHY; DIAGNOSIS; CLASSIFICATION; SUBCOMMITTEE;
D O I
10.1371/journal.pone.0270473
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Meibography is becoming an integral part of dry eye diagnosis. Being objective and repeatable this imaging technique is used to guide treatment decisions and determine the disease status. Especially desirable is the possibility of automatic (or semi-automatic) analysis of a meibomian image for quantification of a particular gland's feature. Recent reports suggest that in addition to the measure of gland atrophy (quantified by the well-established "drop-out area" parameter), the gland's morphological changes may carry equally clinically useful information. Here we demonstrate the novel image analysis method providing detailed information on local deformation of meibomian gland pattern. The developed approach extracts from every Meibomian image a set of six morphometric color-coded maps, each visualizing spatial behavior of different morphometric parameter. A more detailed analysis of those maps was used to perform automatic classification of Meibomian glands images. The method for isolating individual morphometric components from the original meibomian image can be helpful in the diagnostic process. It may help clinicians to see in which part of the eyelid the disturbance is taking place and also to quantify it with a numerical value providing essential insight into Meibomian gland dysfunction pathophysiology.
引用
收藏
页数:16
相关论文
共 40 条
[1]   Meibomian Gland Morphology Is a Sensitive Early Indicator of Meibomian Gland Dysfunction [J].
Adil, Mohammed Yasin ;
Xiao, Jiaxin ;
Olafsson, Jonatan ;
Chen, Xiangjun ;
Lagali, Neil S. ;
Raeder, Sten ;
Utheim, Oygunn A. ;
Dartt, Darlene A. ;
Utheim, Tor P. .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 2019, 200 :16-25
[2]  
Andrews JD, 2020, INVEST OPHTH VIS SCI, V61
[3]   Noncontact infrared meibography to document age-related changes of the meibomian glands in a normal population [J].
Arita, Reiko ;
Itoh, Kouzo ;
Inoue, Kenji ;
Amano, Shiro .
OPHTHALMOLOGY, 2008, 115 (05) :911-915
[4]   Proposed Algorithm for Management of Meibomian Gland Dysfunction Based on Noninvasive Meibography [J].
Arita, Reiko ;
Fukuoka, Shima ;
Kawashima, Motoko .
JOURNAL OF CLINICAL MEDICINE, 2021, 10 (01) :1-10
[5]   Objective image analysis of the meibomian gland area [J].
Arita, Reiko ;
Suehiro, Jun ;
Haraguchi, Tsuyoshi ;
Shirakawa, Rika ;
Tokoro, Hideaki ;
Amano, Shiro .
BRITISH JOURNAL OF OPHTHALMOLOGY, 2014, 98 (06) :746-755
[6]   Association of contact lens-related allergic conjunctivitis with changes in the morphology of meibomian glands [J].
Arita, Reiko ;
Itoh, Kouzo ;
Maeda, Shuji ;
Maeda, Koshi ;
Tomidokoro, Atsuo ;
Amano, Shiro .
JAPANESE JOURNAL OF OPHTHALMOLOGY, 2012, 56 (01) :14-19
[7]   Meibomian Gland Duct Distortion in Patients With Perennial Allergic Conjunctivitis [J].
Arita, Reiko ;
Itoh, Kouzo ;
Maeda, Shuji ;
Maeda, Koshi ;
Furuta, Ayumu ;
Tomidokoro, Atsuo ;
Amano, Shiro .
CORNEA, 2010, 29 (08) :858-860
[8]   Proposed Diagnostic Criteria for Obstructive Meibomian Gland Dysfunction [J].
Arita, Reiko ;
Itoh, Kouzo ;
Maeda, Syuji ;
Maeda, Koshi ;
Furuta, Ayumu ;
Fukuoka, Shima ;
Tomidokoro, Atsuo ;
Amano, Shiro .
OPHTHALMOLOGY, 2009, 116 (11) :2058-2063
[9]  
Celik Turgay., 2013, J Optom, V6, P194, DOI DOI 10.1016/J.OPTOM.2013.09.001
[10]   Fingerprint enhancement using STFT analysis [J].
Chikkerur, Sharat ;
Cartwright, Alexander N. ;
Govindaraju, Venu .
PATTERN RECOGNITION, 2007, 40 (01) :198-211