THE MG-QOL15 JAPANESE VERSION: VALIDATION AND ASSOCIATIONS WITH CLINICAL FACTORS

被引：63

作者：

Masuda, Masayuki ^{[2
]}

Utsugisawa, Kimiaki ^{[1
]}

Suzuki, Shigeaki ^{[3
]}

Nagane, Yuriko ^{[1
]}

Kabasawa, Chiaki ^{[4
]}

Suzuki, Yasushi ^{[5
]}

Shimizu, Yuko ^{[4
]}

Utsumi, Hiroya ^{[2
]}

Fujihara, Kazuo ^{[6
]}

Uchiyama, Shinichiro ^{[4
]}

Suzuki, Norihiro ^{[3
]}

机构：

[1] Hanamaki Gen Hosp, Dept Neurol, Hanamaki 0250075, Japan

[2] Tokyo Med Univ, Dept Neurol, Tokyo, Japan

[3] Keio Univ, Sch Med, Dept Neurol, Tokyo, Japan

[4] Sendai Med Ctr, Dept Neurol, Sendai, Miyagi, Japan

[5] Tohoku Univ, Grad Sch Med, Dept Neurol, Sendai, Miyagi 980, Japan

[6] Tokyo Womens Med Univ, Dept Neurol, Tokyo, Japan

来源：

MUSCLE & NERVE | 2012年 / 46卷 / 02期

关键词：

cross-sectional study; health-related quality of life; myasthenia gravis; questionnaire; validity; QUALITY-OF-LIFE; MYASTHENIA-GRAVIS; OUTCOME MEASURE; ADAPTATION; INSTRUMENT;

D O I：

10.1002/mus.23398

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Introduction: Our study aim was to produce a Japanese translation of the 15-item Myasthenia Gravis Quality-of-Life Scale (MG-QOL15), assess its reliability and validity, and examine clinical factors affecting self-perceived QOL in MG. Methods: We evaluated 327 consecutive patients with MG seen at six neurological centers. All patients completed the Japanese version of the MG-QOL15 (MG-QOL15-J), the Beck Depression Inventory-second edition (BDI-II), and a generic health-related QOL questionnaire, the SF-36. Disease severity was determined according to the Myasthenia Gravis Foundation of America (MGFA) quantitative MG score and the MG composite. Results: The MG-QOL15-J exhibited adequate internal reliability, test-retest repeatability, and concurrent validity with SF-36, disease severity, and known-patient groups categorized by MGFA post-intervention status. Multivariate analysis revealed severity, dose of oral corticosteroids, and BDI-II as independent factors negatively affecting QOL. Conclusion: The MG-QOL15J is anticipated to be a valuable clinical measure of QOL in Japanese patients with MG. Muscle Nerve 46: 166-173, 2012

引用

页码：166 / 173

页数：8

共 27 条

[1] Guidelines for the process of cross-cultural adaptation of self-report measures
Beaton, DE
Bombardier, C
Guillemin, F
Ferraz, MB
[J]. SPINE, 2000, 25 (24) : 3186 - 3191
[2] Beck A.T., 1996, Manual for the BDI-II, DOI DOI 10.1037/T00742-000
[3] Less is more, or almost as much: A 15-item quality-of-life instrument for myasthenia gravis
Burns, Ted M.
Conaway, Mark R.
Cutter, Gary R.
Sanders, Donald B.
[J]. MUSCLE & NERVE, 2008, 38 (02) : 957 - 963
[4] THE MG-QOL15 FOR FOLLOWING THE HEALTH-RELATED QUALITY OF LIFE OF PATIENTS WITH MYASTHENIA GRAVIS
Burns, Ted M.
Grouse, C. K.
Wolfe, Gil I.
Conaway, Mark R.
Sanders, Donald B.
[J]. MUSCLE & NERVE, 2011, 43 (01) : 14 - 18
[5] HISTORY OF OUTCOME MEASURES FOR MYASTHENIA GRAVIS
Burns, Ted M.
[J]. MUSCLE & NERVE, 2010, 42 (01) : 5 - 13
[6] The MG Composite A valid and reliable outcome measure for myasthenia gravis
Burns, Ted M.
Conaway, Mark
Sanders, Donald B.
[J]. NEUROLOGY, 2010, 74 (18) : 1434 - 1440
[7] CONSTRUCT AND CONCURRENT VALIDATION OF THE MG-QOL15 IN THE PRACTICE SETTING
Burns, Ted M.
Grouse, C. K.
Conaway, Mark R.
Sanders, Donald B.
[J]. MUSCLE & NERVE, 2010, 41 (02) : 219 - 226
[8] CONSTRUCTION OF AN EFFICIENT EVALUATIVE INSTRUMENT FOR MYASTHENIA GRAVIS: THE MG COMPOSITE
Burns, Ted M.
Conaway, Mark R.
Cutter, Gary R.
Sanders, Donald B.
[J]. MUSCLE & NERVE, 2008, 38 (06) : 1553 - 1562
[9] Translation, adaptation, and validation of the SF-36 Health Survey for use in Japan
Fukuhara, S
Bito, S
Green, J
Hsiao, A
Kurokawa, K
[J]. JOURNAL OF CLINICAL EPIDEMIOLOGY, 1998, 51 (11) : 1037 - 1044
[10] Fukuhara S., 2004, MANUAL SF 36V2 JAPAN

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