An Exaggerated Hypertensive Response to Glycopyrrolate Therapy for Bradycardia Associated with High-Dose Dexmedetomidine

被引：73

作者：

Mason, Keira P. ^{[1
]}

Zgleszewski, Steven ^{[1
]}

Forman, Roberta E. ^{[2
,3
]}

Stark, Cynthia ^{[2
,3
]}

DiNardo, James A. ^{[1
]}

机构：

[1] Childrens Hosp Boston, Dept Anesthesia Perioperat & Pain Med, Boston, MA 02115 USA

[2] Childrens Hosp Boston, Dept Radiol, Boston, MA 02115 USA

[3] Harvard Univ, Sch Med, Boston, MA USA

来源：

ANESTHESIA AND ANALGESIA | 2009年 / 108卷 / 03期

关键词：

GANGLIONIC BLOCKADE; SEDATION; CHILDREN; DOG;

D O I：

10.1213/ane.0b013e3181948a6f

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

At our institution, high-dose IV dexmedetomidine is used to provide sedation for pediatric patients undergoing nonpainful radiological imaging studies. Some of these patients exhibit marked bradycardia (more than 20% deviation from the lowest age-adjusted normal values) while maintaining an arterial blood pressure within an acceptable normal range. We report on three cases wherein treatment of dexmedetomidine-induced bradycardia with IV glycopyrrolate (5.0 mu g/kg) not only resulting in resolution of bradycardia but also resulting in an exaggerated increase of arterial blood pressure.

引用

页码：906 / 908

页数：3

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