Changes in Molecular Characteristics of Mycoplasma pneumoniae in Clinical Specimens from Children in Beijing between 2003 and 2015

被引：30

作者：

Sun, Hongmei ^{[1
]}

Xue, Guanhua ^{[1
]}

Yan, Chao ^{[1
]}

Li, Shaoli ^{[1
]}

Zhao, Hanqing ^{[1
]}

Feng, Yanling ^{[1
]}

Wang, Liqiong ^{[1
]}

机构：

[1] Capital Inst Pediat, Dept Bacteriol, Beijing, Peoples R China

来源：

PLOS ONE | 2017年 / 12卷 / 01期

基金：

北京市自然科学基金;

关键词：

TANDEM-REPEAT ANALYSIS; UNITED-STATES; SURVEILLANCE; INFECTIONS; STRAINS; JAPAN; CHINA;

D O I：

10.1371/journal.pone.0170253

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The molecular characteristics of 480 Mycoplasma pneumoniae polymerase chain reaction positive specimens (331 were previously reported and 149 were newly reported) collected from pediatric patients in Beijing, China, between 2003 and 2015 were analyzed. Genotype M4-5-7-2/P1 were the most prevalent across the 13-year study period, although the isolation and mutation rates for this genotype varied between the periods 2003-2007, 2008-2013, and 2014-2015. In addition, there was a close association between the M4-5-7-2 genotype and macrolide resistance.

引用

页数：9

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